ID A0A8C7EID2_NEOVI Unreviewed; 690 AA. AC A0A8C7EID2; DT 19-JAN-2022, integrated into UniProtKB/TrEMBL. DT 19-JAN-2022, sequence version 1. DT 13-SEP-2023, entry version 8. DE RecName: Full=F-box/LRR-repeat protein 5 {ECO:0000256|ARBA:ARBA00020540}; DE AltName: Full=F-box and leucine-rich repeat protein 5 {ECO:0000256|ARBA:ARBA00030695}; GN Name=FBXL5 {ECO:0000313|Ensembl:ENSNVIP00000000584.1}; OS Neovison vison (American mink) (Mustela vison). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Mustelinae; OC Neogale. OX NCBI_TaxID=452646 {ECO:0000313|Ensembl:ENSNVIP00000000584.1, ECO:0000313|Proteomes:UP000694425}; RN [1] {ECO:0000313|Ensembl:ENSNVIP00000000584.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (MAY-2023) to UniProtKB. CC -!- PATHWAY: Protein modification; protein ubiquitination. CC {ECO:0000256|ARBA:ARBA00004906}. CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region CC {ECO:0000256|ARBA:ARBA00004556}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSNVIT00000000673.1; ENSNVIP00000000584.1; ENSNVIG00000000490.1. DR GeneTree; ENSGT00390000006172; -. DR UniPathway; UPA00143; -. DR Proteomes; UP000694425; Unplaced. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:InterPro. DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. DR CDD; cd22118; F-box_FBXL5; 1. DR CDD; cd12109; Hr_FBXL5; 1. DR Gene3D; 1.20.1280.50; -; 1. DR Gene3D; 1.20.120.520; nmb1532 protein domain like; 1. DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2. DR InterPro; IPR036047; F-box-like_dom_sf. DR InterPro; IPR001810; F-box_dom. DR InterPro; IPR012312; Hemerythrin-like. DR InterPro; IPR045808; Hr_FBXL5. DR InterPro; IPR001611; Leu-rich_rpt. DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp. DR InterPro; IPR032675; LRR_dom_sf. DR PANTHER; PTHR13318:SF19; F-BOX/LRR-REPEAT PROTEIN 5; 1. DR PANTHER; PTHR13318; UNCHARACTERIZED; 1. DR Pfam; PF12937; F-box-like; 1. DR Pfam; PF01814; Hemerythrin; 1. DR Pfam; PF13516; LRR_6; 3. DR SMART; SM00256; FBOX; 1. DR SMART; SM00367; LRR_CC; 4. DR SUPFAM; SSF81383; F-box domain; 1. DR SUPFAM; SSF52047; RNI-like; 1. DR PROSITE; PS50181; FBOX; 1. PE 4: Predicted; KW Iron {ECO:0000256|ARBA:ARBA00023004}; KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}; KW Reference proteome {ECO:0000313|Proteomes:UP000694425}; KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}; KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}. FT DOMAIN 202..248 FT /note="F-box" FT /evidence="ECO:0000259|PROSITE:PS50181" SQ SEQUENCE 690 AA; 78207 MW; FF0746B89110F593 CRC64; MAPFPEEVDV FTAPHWRMKQ LVGLYCDKLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI ENEYIIGLLQ QRSQTIYNVH SDNKLSEMLS LFEKGLKNVK NECEQLNYAK QLKERLEAFT RDFLPHMKEE EEVFQPMLME YFTYEELKDI KKKVIAQHCS QKDTAELLRG LSLWNQAEER QKFFKYSVDE KSDKEAEVSE QATGITHLPP EVMLSIFSYL NPQELCRCSQ VSTKWSQLAK TGSLWKHLYP VHWARGDWYS GPATELDTEP DEEWVKNRKD ESRAFQEWDE DADIDESEES AEESIAISIA QMEKRLLHGL IHNVLPYVGT SVKTIVLAYS SAVSSKMVRQ ILELCPNLEH LDLTQTDISD SAFDSWSWLG CCQSLRHLDL SGCEKITDVA LEKISRALGI LTSHQSGLLK TTSKITSTTW KNKDITMQST KQYTCLHDLT NKGIGEEMDN EHPWTKTVSS DSFTSPYVWM LDAEDLADIE DAVEWRHRNV ESLCVMETAS NFSCSSSGCY SKDIVGLRTS VCWQQHCASP AFAYCGHSFC CTGTALRTMS ALPESSALCK KASRTRLLRG QDLIYSGSEK SEQETGRVLL FLSLSGCYQI TDHGLRVLTL GGGLPYLEHL NLSGCLTVTG AGLQDLVSAC PSLNDEYFYY CDNINGPHAD TASGCQNLQC GFRACCRSGE //