ID   A0A8B3QP47_KLEPN        Unreviewed;       429 AA.
AC   A0A8B3QP47;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   03-AUG-2022, entry version 4.
DE   SubName: Full=MFS transporter {ECO:0000313|EMBL:RWT63448.1};
GN   ORFNames=DN601_07740 {ECO:0000313|EMBL:RWT63448.1};
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573 {ECO:0000313|EMBL:RWT63448.1, ECO:0000313|Proteomes:UP000288743};
RN   [1] {ECO:0000313|EMBL:RWT63448.1, ECO:0000313|Proteomes:UP000288743}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GEO_28_Up_A {ECO:0000313|EMBL:RWT63448.1,
RC   ECO:0000313|Proteomes:UP000288743};
RA   Mathys D.A., Mollenkopf D.F., Feicht S.M., Adams R.J., Albers A.L.,
RA   Grooters S.V., Stuever D.M., Daniels J.B., Wittum T.E.;
RT   "Carbapenemase-producing Enterobacteriaceae present in wastewater treatment
RT   plant effluent and nearby surface waters in the US.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWT63448.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QKPF01000004; RWT63448.1; -; Genomic_DNA.
DR   RefSeq; WP_004201705.1; NZ_UKYW01000001.1.
DR   GeneID; 64294302; -.
DR   Proteomes; UP000288743; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        141..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          17..420
FT                   /note="MFS"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   429 AA;  45956 MW;  FDDD5424BF0E1B86 CRC64;
     MSNTLLESVV KKNRARLIPF MLALYVLAFL DRSNIGFAKE TYQLDTGLSN EAYALGAGIF
     FVVYAFLGVP ANLLMRKFGA RKWIGCTTLL WGVLSAAMAW ADTEAKFLLV RTLLGAAEAG
     FFPGMIYLTS QWFPQQNRAS IMGLFYMGAP LALTLGSPLS GALLEMHGFM GHPGWFWMFV
     IEGLLAVAAG AFTFFWLDDS PQHARFLSAA EKQALIGELA REEEKKVTSR LSDALRNGRV
     WQLALIYMTI QVAVYGLIFF LPTQVAALLG TKVGFIASVV TAIPWVAALF GTWLIPRYSD
     RTGERRNIAA LTLLAAAVGI AVSGLVAPVL AIIALCVAAV GVIAVQPVFW TMPTQLLSGT
     ALAAGIGFVN LFGAIGGFLA PIVRVQAETL FASSAAGLLT LAGVAIVGVI IIFSLSLTRA
     VPQRGSVQH
//