ID A0A847ZDE6_9BACT Unreviewed; 245 AA. AC A0A847ZDE6; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 27-NOV-2024, entry version 12. DE SubName: Full=Fic family protein {ECO:0000313|EMBL:NMC91511.1}; GN ORFNames=GYA67_07585 {ECO:0000313|EMBL:NMC91511.1}; OS Smithella sp. OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Smithellaceae; OC Smithella. OX NCBI_TaxID=2053614 {ECO:0000313|EMBL:NMC91511.1, ECO:0000313|Proteomes:UP000581623}; RN [1] {ECO:0000313|EMBL:NMC91511.1, ECO:0000313|Proteomes:UP000581623} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AS4AglBPMA_11 {ECO:0000313|EMBL:NMC91511.1}; RX PubMed=32123542; RA Campanaro S., Treu L., Rodriguez-R L.M., Kovalovszki A., Ziels R.M., RA Maus I., Zhu X., Kougias P.G., Basile A., Luo G., Schluter A., RA Konstantinidis K.T., Angelidaki I.; RT "New insights from the biogas microbiome by comprehensive genome-resolved RT metagenomics of nearly 1600 species originating from multiple anaerobic RT digesters."; RL Biotechnol. Biofuels 13:25-20(2020). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:NMC91511.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JAAZOZ010000203; NMC91511.1; -; Genomic_DNA. DR AlphaFoldDB; A0A847ZDE6; -. DR Proteomes; UP000581623; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0070733; F:AMPylase activity; IEA:UniProt. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR Gene3D; 1.10.3290.10; Fido-like domain; 1. DR InterPro; IPR003812; Fido. DR InterPro; IPR036597; Fido-like_dom_sf. DR InterPro; IPR040198; Fido_containing. DR PANTHER; PTHR13504; FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145; 1. DR PANTHER; PTHR13504:SF34; PROTEIN ADENYLYLTRANSFERASE FICD; 1. DR Pfam; PF02661; Fic; 1. DR SUPFAM; SSF140931; Fic-like; 1. DR PROSITE; PS51459; FIDO; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|PIRSR:PIRSR640198-2}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR640198-2}. FT DOMAIN 94..230 FT /note="Fido" FT /evidence="ECO:0000259|PROSITE:PS51459" FT ACT_SITE 173 FT /evidence="ECO:0000256|PIRSR:PIRSR640198-1" FT BINDING 177..184 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2" FT SITE 45 FT /note="Important for autoinhibition of adenylyltransferase FT activity" FT /evidence="ECO:0000256|PIRSR:PIRSR640198-3" SQ SEQUENCE 245 AA; 27962 MW; D08F792423C097EB CRC64; MKDILKKIDS IKTKIDAHRP LDSHMVRELR EYFRIGMTYS SNALEGNSLT ETETKIVIED GITIGGKPVK DHLEALGHSE AYDLLFRLAK HQDISEANIK ELHRLFYYRI DEDQAGKYRK QKVIITGTTF IPPAPEQIPD LMKSFVARIP DDRSKHHPVE YAAILHRKLV TVHPFIDGNG RAARLLMNLA LLQAGYPVAI IPPVLRRDYL DTLNKTHKGD DKAFNKFIAG VCYESSKEYL RLLEG //