ID A0A842GY18_9NOCA Unreviewed; 345 AA. AC A0A842GY18; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 22-FEB-2023, entry version 6. DE SubName: Full=NAD(P)-dependent alcohol dehydrogenase {ECO:0000313|EMBL:MBC2588404.1}; GN ORFNames=H0B42_08005 {ECO:0000313|EMBL:MBC2588404.1}; OS Rhodococcus aetherivorans. OC Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Rhodococcus. OX NCBI_TaxID=191292 {ECO:0000313|EMBL:MBC2588404.1, ECO:0000313|Proteomes:UP000579733}; RN [1] {ECO:0000313|EMBL:MBC2588404.1, ECO:0000313|Proteomes:UP000579733} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=4CI {ECO:0000313|EMBL:MBC2588404.1, RC ECO:0000313|Proteomes:UP000579733}; RA Chen W., Faulkner N., Smith C., Hyman M.; RT "Draft genome sequence of four isobutane-metabolizing strains capable of RT cometabolically degrading diverse ether contaminants."; RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256|RuleBase:RU361277}; CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase CC family. {ECO:0000256|RuleBase:RU361277}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:MBC2588404.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JACCFD010000002; MBC2588404.1; -; Genomic_DNA. DR AlphaFoldDB; A0A842GY18; -. DR Proteomes; UP000579733; Unassembled WGS sequence. DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR CDD; cd05284; arabinose_DH_like; 1. DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1. DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1. DR InterPro; IPR013149; ADH-like_C. DR InterPro; IPR013154; ADH_N. DR InterPro; IPR002328; ADH_Zn_CS. DR InterPro; IPR011032; GroES-like_sf. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR020843; PKS_ER. DR PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1. DR PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1. DR Pfam; PF08240; ADH_N; 1. DR Pfam; PF00107; ADH_zinc_N; 1. DR SMART; SM00829; PKS_ER; 1. DR SUPFAM; SSF50129; GroES-like; 1. DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1. DR PROSITE; PS00059; ADH_ZINC; 1. PE 3: Inferred from homology; KW Metal-binding {ECO:0000256|RuleBase:RU361277}; KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}; KW Zinc {ECO:0000256|RuleBase:RU361277}. FT DOMAIN 10..343 FT /note="Enoyl reductase (ER)" FT /evidence="ECO:0000259|SMART:SM00829" SQ SEQUENCE 345 AA; 35192 MW; 90BF37E6FA00C8B5 CRC64; MKAVQYTEIG SEPVVVDIPT PAPGPGEILL KVTAAGLCHS DIFVMDMPAA QYAYGLPLTL GHEGVGTVAE LGEGVTGFGV GDAVAVYGPW GCGACHACAR GRENYCTRAA DLGITPPGLG SPGSMAEYMI VDSARHLVPI GDLDPVAAAP LTDAGLTPYH AISRVLPLLG PGSTAVVIGV GGLGHVGIQI LRAVSAARVI AVDLDDDRLA LAREVGADAA VMSGAGAADA IRELTGGQGA TAVFDFVGAQ STIDTAQQVV TVDGHISVVG IHAGAHAKVG FFMIPFGASV VTPYWGTRSE LMEVVALARA GRLDIHTETF TLDEGPAAYR RLREGSIRGR GVVVP //