ID A0A840BIG2_9RHOO Unreviewed; 115 AA. AC A0A840BIG2; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 14-DEC-2022, entry version 5. DE RecName: Full=Succinate dehydrogenase hydrophobic membrane anchor subunit {ECO:0000256|ARBA:ARBA00019425}; GN ORFNames=GGR36_000670 {ECO:0000313|EMBL:MBB4011362.1}; OS Niveibacterium umoris. OC Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales; OC Rhodocyclaceae; Niveibacterium. OX NCBI_TaxID=1193620 {ECO:0000313|EMBL:MBB4011362.1, ECO:0000313|Proteomes:UP000561045}; RN [1] {ECO:0000313|EMBL:MBB4011362.1, ECO:0000313|Proteomes:UP000561045} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 106739 {ECO:0000313|EMBL:MBB4011362.1, RC ECO:0000313|Proteomes:UP000561045}; RA Goeker M.; RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the RT most valuable type-strain genomes for metagenomic binning, comparative RT biology and taxonomic classification."; RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Membrane-anchoring subunit of succinate dehydrogenase (SDH). CC {ECO:0000256|ARBA:ARBA00004050}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|PIRSR:PIRSR000169-2}; CC Note=The heme is bound between the two transmembrane subunits. CC {ECO:0000256|PIRSR:PIRSR000169-2}; CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle. CC {ECO:0000256|ARBA:ARBA00005163}. CC -!- SUBUNIT: Part of an enzyme complex containing four subunits: a CC flavoprotein, an iron-sulfur protein, plus two membrane-anchoring CC proteins, SdhC and SdhD. {ECO:0000256|ARBA:ARBA00011558}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:MBB4011362.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JACIET010000001; MBB4011362.1; -; Genomic_DNA. DR AlphaFoldDB; A0A840BIG2; -. DR UniPathway; UPA00223; -. DR Proteomes; UP000561045; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0000104; F:succinate dehydrogenase activity; IEA:InterPro. DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway. DR Gene3D; 1.20.1300.10; -; 1. DR InterPro; IPR034804; SQR/QFR_C/D. DR InterPro; IPR014312; Succ_DH_anchor. DR InterPro; IPR000701; SuccDH_FuR_B_TM-su. DR PANTHER; PTHR38689; SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT; 1. DR Pfam; PF01127; Sdh_cyt; 1. DR PIRSF; PIRSF000169; SDH_D; 1. DR SUPFAM; SSF81343; Fumarate reductase respiratory complex transmembrane subunits; 1. DR TIGRFAMs; TIGR02968; succ_dehyd_anc; 1. PE 4: Predicted; KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR000169-2}; KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR000169-2}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|PIRSR:PIRSR000169-2}; KW Reference proteome {ECO:0000313|Proteomes:UP000561045}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 21..44 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 50..70 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 91..113 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT BINDING 71 FT /ligand="heme" FT /ligand_id="ChEBI:CHEBI:30413" FT /ligand_note="ligand shared with second transmembrane FT subunit" FT /ligand_part="Fe" FT /ligand_part_id="ChEBI:CHEBI:18248" FT /note="axial binding residue" FT /evidence="ECO:0000256|PIRSR:PIRSR000169-2" FT BINDING 83 FT /ligand="a ubiquinone" FT /ligand_id="ChEBI:CHEBI:16389" FT /evidence="ECO:0000256|PIRSR:PIRSR000169-1" SQ SEQUENCE 115 AA; 13177 MW; 9C7CEE3E8CA8EB61 CRC64; MQKRIVVGAH YGLRDWIAQR VTATVMALYS VFFVINLLCL PAFTSDAWRA MFAGGFMRFA TFLFWLSLFF HAWVGVRDIF MDYVKPVGVR LALHSVVALL LIGYAGWAAQ ILWRL //