ID A0A832VYQ2_METTF Unreviewed; 642 AA. AC A0A832VYQ2; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 22-FEB-2023, entry version 6. DE SubName: Full=IGHMBP2 family helicase {ECO:0000313|EMBL:HIH71028.1}; DE EC=3.6.4.12 {ECO:0000313|EMBL:HIH71028.1}; GN ORFNames=HA301_03095 {ECO:0000313|EMBL:HIH71028.1}; OS Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum). OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria; OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter. OX NCBI_TaxID=145262 {ECO:0000313|EMBL:HIH71028.1, ECO:0000313|Proteomes:UP000644706}; RN [1] {ECO:0000313|EMBL:HIH71028.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA12524 {ECO:0000313|EMBL:HIH71028.1}; RX DOI=10.1101/2020.03.01.972265; RA Rinke C., Chuvochina M., Mussig A.J., Chaumeil P.-A., Waite D.W., RA Whitman W.B., Parks D.H., Hugenholtz P.; RT "A rank-normalized archaeal taxonomy based on genome phylogeny resolves RT widespread incomplete and uneven classifications."; RL bioRxiv 0:0-0(2020). CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. CC {ECO:0000256|ARBA:ARBA00007913}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:HIH71028.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DUIJ01000037; HIH71028.1; -; Genomic_DNA. DR AlphaFoldDB; A0A832VYQ2; -. DR Proteomes; UP000644706; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR CDD; cd18808; SF1_C_Upf1; 1. DR Gene3D; 2.40.30.270; -; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR041679; DNA2/NAM7-like_C. DR InterPro; IPR041677; DNA2/NAM7_AAA_11. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR004483; SMUBP-2/Hcs1-like. DR PANTHER; PTHR43788:SF8; DNA-BINDING PROTEIN SMUBP-2; 1. DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1. DR Pfam; PF13086; AAA_11; 1. DR Pfam; PF13087; AAA_12; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR TIGRFAMs; TIGR00376; putative DNA helicase; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000313|EMBL:HIH71028.1}; KW Helicase {ECO:0000313|EMBL:HIH71028.1}; KW Hydrolase {ECO:0000313|EMBL:HIH71028.1}; KW Nucleotide-binding {ECO:0000313|EMBL:HIH71028.1}. FT DOMAIN 171..420 FT /note="AAA+ ATPase" FT /evidence="ECO:0000259|SMART:SM00382" SQ SEQUENCE 642 AA; 72649 MW; 616BC73A33BECE7E CRC64; MEREAEISAM MNEIRRLSPR QRERAGRAVN GLNGKITGRE LGFHLVKYGR RDPIDTQISV GDLVLISRGN PLRSDLTGTV AMKGKRFLVV ALEHVPGWAL KNVRIDLYAN DVTFQRMIDN LKSPTRNVLR VLGFLCGTEK PSDGVDGLDF QAVDPELNES QRDAIRMALG SEDFFLIHGP FGTGKTRTLH ELIRQEVMRG SRVLVTAESN AAVDNLLEGI AGHVKCVRLG HPQRVSRENL METLAYKIEN HPEYRKVQEY QEKIDELIEE RERHQKPTPQ IRRGLSDTQI LINATKRRGA RGISPNVMIS MARWIETNQR IDDLHSKLQE AEMRIADRIL RESQVVLSTN SSAALEYIDG LRFDVAIVDE ASQATIPSIL IPLARAPRFI LAGDHRQLPP TILSRDASEL ERTLFEELIE RHPGRSRMLK CQYRMHPAIM EFPNREFYDG RIRAHPSLEG ISIRDIIEDV PDSDICQKLA DPDPVLFIDT SGLDGCERRL KGSTSIQNPL EADLAVIISR SLMRMGVKPE EIGIITPYDD QVDLISSMID VEVNSVDGFQ GREKDVIIIS MVRSNRNGSI GFLKDLRRLN VSLTRARRKL IIIGDSRTLS AHPSYRRLTE FCRKRGFLDE PGLDEVMKWG AS //