ID A0A832T726_PYRHR Unreviewed; 409 AA. AC A0A832T726; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 24-JAN-2024, entry version 8. DE RecName: Full=DNA repair protein {ECO:0000256|HAMAP-Rule:MF_02096}; GN ORFNames=HA331_08565 {ECO:0000313|EMBL:HII61771.1}; OS Pyrococcus horikoshii. OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; OC Pyrococcus. OX NCBI_TaxID=53953 {ECO:0000313|EMBL:HII61771.1, ECO:0000313|Proteomes:UP000617544}; RN [1] {ECO:0000313|EMBL:HII61771.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBA8834 {ECO:0000313|EMBL:HII61771.1}; RX DOI=10.1101/2020.03.01.972265; RA Rinke C., Chuvochina M., Mussig A.J., Chaumeil P.-A., Waite D.W., RA Whitman W.B., Parks D.H., Hugenholtz P.; RT "A rank-normalized archaeal taxonomy based on genome phylogeny resolves RT widespread incomplete and uneven classifications."; RL bioRxiv 0:0-0(2020). CC -!- FUNCTION: Involved in DNA damage repair. {ECO:0000256|HAMAP- CC Rule:MF_02096}. CC -!- SIMILARITY: Belongs to the Nre family. {ECO:0000256|HAMAP- CC Rule:MF_02096}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_02096}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:HII61771.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DUJN01000007; HII61771.1; -; Genomic_DNA. DR RefSeq; WP_010885913.1; NZ_DUJN01000007.1. DR AlphaFoldDB; A0A832T726; -. DR GeneID; 1442695; -. DR OMA; PVGVWQI; -. DR Proteomes; UP000617544; Unassembled WGS sequence. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule. DR HAMAP; MF_02096; Nre; 1. DR InterPro; IPR033167; Nre. DR InterPro; IPR006979; Nre_C. DR InterPro; IPR006978; Nre_N. DR PANTHER; PTHR38136; DNA REPAIR PROTEIN; 1. DR PANTHER; PTHR38136:SF2; DNA REPAIR PROTEIN; 1. DR Pfam; PF04895; Nre_C; 1. DR Pfam; PF04894; Nre_N; 1. PE 3: Inferred from homology; KW DNA damage {ECO:0000256|HAMAP-Rule:MF_02096}; KW DNA repair {ECO:0000256|HAMAP-Rule:MF_02096}. FT DOMAIN 18..283 FT /note="Archaeal Nre N-terminal" FT /evidence="ECO:0000259|Pfam:PF04894" FT DOMAIN 295..404 FT /note="Archaeal Nre C-terminal" FT /evidence="ECO:0000259|Pfam:PF04895" SQ SEQUENCE 409 AA; 46875 MW; 4CFE53A4475232B7 CRC64; MIKLNSNICA ICKGRKLLCG RPVCPILEKI RIAREVTPLV NREDIFGSSP PSVFVGEYGY PKVRIGPLVP PIEGDTSYLD NPLKWENARI EDVIKFRSIL VLGQTRVHID LRRSDRIIEE LQELAMSIKP IDTEMLLKRK PILKVIPSEF APPLGPSGEV KNFEIAENPK VPKKVERVVG DEIKAKDAVI TLYESGFDEY YIIRLLSVGL LGLKPRIVPT RWSITAVQDT LGNYLRKSIL NFEPIETYEV YTSEFLGNRY VILLMPRRYS FELLEVWLKG SLFGSEDPVV LHDCEDYRGI KGYAEETTGA YYAARLSVLE HLRRRKRQAS AIVFREVTPA YYTPVGVWQI RVGVKKALEG IPEKFYTLED ALNRLRVKLK HPLERYLARS WILKQLNQRS ITSFLGVRS //