ID A0A828TR35_STREE Unreviewed; 74 AA. AC A0A828TR35; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 19-JAN-2022, entry version 2. DE RecName: Full=Acyl carrier protein {ECO:0000256|HAMAP-Rule:MF_01217}; DE Short=ACP {ECO:0000256|HAMAP-Rule:MF_01217}; GN Name=acpP {ECO:0000256|HAMAP-Rule:MF_01217}; GN ORFNames=SPAR70_0319 {ECO:0000313|EMBL:EHD61425.1}; OS Streptococcus pneumoniae GA41410. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; OC Streptococcus. OX NCBI_TaxID=760811 {ECO:0000313|EMBL:EHD61425.1, ECO:0000313|Proteomes:UP000003388}; RN [1] {ECO:0000313|EMBL:EHD61425.1, ECO:0000313|Proteomes:UP000003388} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GA41410 {ECO:0000313|EMBL:EHD61425.1, RC ECO:0000313|Proteomes:UP000003388}; RA Chancey S., Kumar N., Sengamalay N., Matthews C., Hine E., Pallavajjal A., RA Abolude O., Daugherty S.C., Sadzewicz L., Tallon L.J., Farley M.M., RA Baughman W., McGee L., Stephens D.S., Tettelin H.; RT "Genomic Sequence of Streptococcus pneumoniae GA41410."; RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Carrier of the growing fatty acid chain in fatty acid CC biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01217}. CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis. {ECO:0000256|HAMAP- CC Rule:MF_01217}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01217}. CC -!- PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine CC of apo-ACP by AcpS. This modification is essential for activity because CC fatty acids are bound in thioester linkage to the sulfhydryl of the CC prosthetic group. {ECO:0000256|HAMAP-Rule:MF_01217}. CC -!- SIMILARITY: Belongs to the acyl carrier protein (ACP) family. CC {ECO:0000256|HAMAP-Rule:MF_01217}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:EHD61425.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AGOJ01000007; EHD61425.1; -; Genomic_DNA. DR UniPathway; UPA00094; -. DR Proteomes; UP000003388; Unassembled WGS sequence. DR Gene3D; 1.10.1200.10; -; 1. DR HAMAP; MF_01217; Acyl_carrier; 1. DR InterPro; IPR036736; ACP-like_sf. DR InterPro; IPR003231; Acyl_carrier. DR InterPro; IPR009081; PP-bd_ACP. DR PANTHER; PTHR20863; PTHR20863; 1. DR Pfam; PF00550; PP-binding; 1. DR SUPFAM; SSF47336; SSF47336; 1. DR PROSITE; PS50075; CARRIER; 1. PE 3: Inferred from homology; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01217}; KW Fatty acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_01217}; KW Fatty acid metabolism {ECO:0000256|HAMAP-Rule:MF_01217}; KW Lipid biosynthesis {ECO:0000256|HAMAP-Rule:MF_01217}; KW Lipid metabolism {ECO:0000256|HAMAP-Rule:MF_01217}; KW Phosphopantetheine {ECO:0000256|HAMAP-Rule:MF_01217, ECO:0000256|PROSITE- KW ProRule:PRU00258}; Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_01217}. FT DOMAIN 1..73 FT /note="Carrier" FT /evidence="ECO:0000259|PROSITE:PS50075" FT MOD_RES 35 FT /note="O-(pantetheine 4'-phosphoryl)serine" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01217, FT ECO:0000256|PROSITE-ProRule:PRU00258" SQ SEQUENCE 74 AA; 8268 MW; E2E9A78567090C14 CRC64; MAVFEKVQEI IVEELGKDAS EVTLESTFDD LDADSLDLFQ VISEIEDAFD IQIEAENDLK TVGDLVAYVE EQAK //