ID   A0A826Y7Z5_ECOLX        Unreviewed;       667 AA.
AC   A0A826Y7Z5;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   12-OCT-2022, entry version 5.
DE   SubName: Full=Replication endonuclease {ECO:0000313|EMBL:EFD0797311.1};
GN   ORFNames=CR628_005097 {ECO:0000313|EMBL:EFC8022822.1}, FE584_26280
GN   {ECO:0000313|EMBL:EFD0789583.1}, FE587_14775
GN   {ECO:0000313|EMBL:EFD0797311.1};
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562 {ECO:0000313|EMBL:EFD0797311.1, ECO:0000313|Proteomes:UP000555266};
RN   [1] {ECO:0000313|Proteomes:UP000555266, ECO:0000313|Proteomes:UP000566302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2012EL-1595-sc6 {ECO:0000313|EMBL:EFD0789583.1,
RC   ECO:0000313|Proteomes:UP000566302}, 2012EL-1596-sc1
RC   {ECO:0000313|EMBL:EFD0797311.1, ECO:0000313|Proteomes:UP000555266},
RC   and 2017EL-1017b {ECO:0000313|EMBL:EFC8022822.1,
RC   ECO:0000313|Proteomes:UP000518092};
RG   PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA   Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA   Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL   Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possible endonuclease which induces a single-strand cut and
CC       initiates DNA replication. {ECO:0000256|ARBA:ARBA00003293}.
CC   -!- SIMILARITY: Belongs to the phage GPA family.
CC       {ECO:0000256|ARBA:ARBA00009260}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFD0797311.1}.
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DR   EMBL; AASIMK010000095; EFC8022822.1; -; Genomic_DNA.
DR   EMBL; AASDRF010000103; EFD0789583.1; -; Genomic_DNA.
DR   EMBL; AASDRG010000020; EFD0797311.1; -; Genomic_DNA.
DR   Proteomes; UP000518092; Unassembled WGS sequence.
DR   Proteomes; UP000555266; Unassembled WGS sequence.
DR   Proteomes; UP000566302; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR008766; Replication_gene_A.
DR   Pfam; PF05840; Phage_GPA; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759,
KW   ECO:0000313|EMBL:EFD0797311.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722}.
SQ   SEQUENCE   667 AA;  75421 MW;  966B750FAC69A145 CRC64;
     MKTESAILTA YNAIDAASVA LGRPCLTLPE REHFRTERDV ATRNLATLSR QYRDEVGTLS
     AQLALPRNTQ VDRVIYGINC TDFSLTDRGR AAGLVSQFGS FSFTVAHAFC RLVYQLGVKN
     SLMALESAHR FAFFNQDGDP YEFSLFCTDE QIAEVADSVV RDCLVSRAIY SDVPEHHLLN
     VMAYFQAISG FDFAPVYATY HERYGDEGLL KRLTDLAFVT RFLRVIRDQR VNEVCRMLGI
     LNRNAPYISD WHRDLFAVRS KRVKKYLRSS GVFDAFNELV CTLEDAHNAS VSNPKNRIAE
     LCVRGKAVCE LSEDMGLSGY FIVLTTPSRF HPTTSFKVAG KWHSRPNKKW WEAGCPTVKD
     SHAWLNTVWR RVCRRLDKAG IQIPGLRTVE PHADGTTHWN FLIYCNPHES ATVLAIFREE
     AMRDEPDEKG AKEHRIRIEA IDPEKGDGFR YIVKYITKMA GDVSADGITA LNDRYSARSF
     CDAVSRAACW QKATRLRLFQ FFGVPSVTAY RQMRSFRAPL EAHHINMQQF TPQQVAELEA
     IRMACDAGDF RTYILLNGGF FCSERLLRPF YVQPQEGGKP RFNRYGEPCA PVISGFMFGP
     VPVITRFMGC VVRRMTPAEK IRAEEVRSGS SYESVFISSA SRHRTTRSRA AGGGGEADPW
     TCDNNCP
//