ID A0A821ZT08_9NEOB Unreviewed; 636 AA. AC A0A821ZT08; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 24-JAN-2024, entry version 6. DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675}; DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675}; GN ORFNames=RIMITATOR_LOCUS6647609 {ECO:0000313|EMBL:CAF4993226.1}; OS Ranitomeya imitator (mimic poison frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Neobatrachia; Hyloidea; Dendrobatidae; Dendrobatinae; OC Ranitomeya. OX NCBI_TaxID=111125 {ECO:0000313|EMBL:CAF4993226.1}; RN [1] {ECO:0000313|EMBL:CAF4993226.1} RP NUCLEOTIDE SEQUENCE. RA Stuckert A.; RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues CC in beta-D-galactosides.; EC=3.2.1.23; CC Evidence={ECO:0000256|RuleBase:RU000675}; CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family. CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:CAF4993226.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAJOBX010018335; CAF4993226.1; -; Genomic_DNA. DR AlphaFoldDB; A0A821ZT08; -. DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2. DR Gene3D; 3.20.20.80; Glycosidases; 1. DR InterPro; IPR026283; B-gal_1-like. DR InterPro; IPR048912; BetaGal1-like_ABD1. DR InterPro; IPR048913; BetaGal_gal-bd. DR InterPro; IPR008979; Galactose-bd-like_sf. DR InterPro; IPR031330; Gly_Hdrlase_35_cat. DR InterPro; IPR019801; Glyco_hydro_35_CS. DR InterPro; IPR001944; Glycoside_Hdrlase_35. DR InterPro; IPR017853; Glycoside_hydrolase_SF. DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1. DR PANTHER; PTHR23421:SF53; BETA-GALACTOSIDASE-1-LIKE PROTEIN 2; 1. DR Pfam; PF21317; BetaGal_ABD_1; 1. DR Pfam; PF21467; BetaGal_gal-bd; 1. DR Pfam; PF01301; Glyco_hydro_35; 1. DR PIRSF; PIRSF006336; B-gal; 1. DR PRINTS; PR00742; GLHYDRLASE35. DR SUPFAM; SSF51445; (Trans)glycosidases; 1. DR SUPFAM; SSF49785; Galactose-binding domain-like; 1. DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1. PE 3: Inferred from homology; KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675}. FT DOMAIN 53..366 FT /note="Glycoside hydrolase 35 catalytic" FT /evidence="ECO:0000259|Pfam:PF01301" FT DOMAIN 425..524 FT /note="Beta-galactosidase 1-like first all-beta" FT /evidence="ECO:0000259|Pfam:PF21317" FT DOMAIN 548..607 FT /note="Beta-galactosidase galactose-binding" FT /evidence="ECO:0000259|Pfam:PF21467" FT ACT_SITE 201 FT /note="Proton donor" FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1" FT ACT_SITE 277 FT /note="Nucleophile" FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1" SQ SEQUENCE 636 AA; 72219 MW; 714EAAAC0D0CC7A1 CRC64; MPKWSLRRRP GRTLGLLLLL VLSFLVLRRL NWTSVLPLWL QRQRLGLRTK GPNFMLEDST FQILGGSIHY FRVPREYWRD RLLKLKACGL NTLTTYVPWN LHEPERGKFD FSGNLDLEAF IWLAAKIGLW VILRPGPYIC SEIDLGGLPS WLLQDPDMKL RTTYPGFTKA VDLYFDHLMS RVVPLQYKHG GPIIAVQVEN EYGSYNGDHA YMPYIKKALE DRGIIEMLLT SDNKDGLEKG VVDGVLATIN LQSQQELVAL NSILLSIQGI QPKMVMEYWT GWFDSWGGSH NILDSSEVLQ TVSAIIKDGS SINLYMFHGG TNFGFINGAM HFGDYKADVT SYDYDAILTE AGDYTAKYTK LRELFGTFSG VPPPPPPELT AKMVYEPVTP SFYLSLWDAL LYMDKPITSE IPINMENLPV NNGNGQAFGY VLYETTIFSS GVLSGLVRDR GQVFLNRVSI GFLDYTTTKI TIPLTQGYTI LRILVENRGR VNYGNNIDSQ RKGLIGNLYL NNKPLKNFKI YSLDMTKQFF QRFDMDKWSV VPKEITFPAF FLGTLSVGIY PSDTFLKLEG WVKGVVLVND HNLGRYWNVG PQETLYLPGV WLDKGLNKVI IFEETMAGSM VQSTDIPHLG RNQYVN //