ID A0A821YU06_9NEOB Unreviewed; 221 AA. AC A0A821YU06; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 25-MAY-2022, entry version 3. DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059}; GN ORFNames=RIMITATOR_LOCUS6008127 {ECO:0000313|EMBL:CAF4965124.1}; OS Ranitomeya imitator (mimic poison frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Neobatrachia; Hyloidea; Dendrobatidae; Dendrobatinae; OC Ranitomeya. OX NCBI_TaxID=111125 {ECO:0000313|EMBL:CAF4965124.1, ECO:0000313|Proteomes:UP000663875}; RN [1] {ECO:0000313|EMBL:CAF4965124.1} RP NUCLEOTIDE SEQUENCE. RA Stuckert A.; RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223, CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17; CC Evidence={ECO:0000256|RuleBase:RU362059}; CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362059}; Single- CC pass membrane protein {ECO:0000256|RuleBase:RU362059}. CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family. CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:CAF4965124.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAJOBX010015765; CAF4965124.1; -; Genomic_DNA. DR Proteomes; UP000663875; Unassembled WGS sequence. DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro. DR CDD; cd03784; GT1_Gtf-like; 1. DR InterPro; IPR002213; UDP_glucos_trans. DR InterPro; IPR035595; UDP_glycos_trans_CS. DR Pfam; PF00201; UDPGT; 1. DR PROSITE; PS00375; UDPGT; 1. PE 3: Inferred from homology; KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676, KW ECO:0000256|RuleBase:RU003718}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362059}; KW Reference proteome {ECO:0000313|Proteomes:UP000663875}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU362059}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|RuleBase:RU362059}. FT TRANSMEM 186..212 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362059" FT DOMAIN 49..92 FT /note="UDPGT" FT /evidence="ECO:0000259|PROSITE:PS00375" SQ SEQUENCE 221 AA; 25397 MW; 2E79CF00EB6B24C3 CRC64; MISSLPILEF VKEMNDGFAK IRQKVIWRYK RSHWPKEVDV APNVRLVDWL SQNDLLGQPK VRLLVTHGGM NSLMEAVYHG VPVVGIPLFG DQYENLIRIK AKNMGTFIPP EEMEAESFAN SMREVIENSR YKTSAMKLSV ILRSRPFPPE RQLLGWVEHI LQSGGGGHLR PYSYQQPWYQ RHLLDVILFI STIVAAVVYL TVKVCTVLLS FLPPNRKQKL N //