ID A0A820RI30_9BILA Unreviewed; 336 AA. AC A0A820RI30; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 14-DEC-2022, entry version 5. DE RecName: Full=Notch {ECO:0000256|Google:UnProtein}; DE Flags: Fragment; GN ORFNames=OVN521_LOCUS37131 {ECO:0000313|EMBL:CAF4438142.1}; OS Rotaria magnacalcarata. OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria; OC Bdelloidea; Rotaria. OX NCBI_TaxID=392030 {ECO:0000313|EMBL:CAF4438142.1, ECO:0000313|Proteomes:UP000663866}; RN [1] {ECO:0000313|EMBL:CAF4438142.1} RP NUCLEOTIDE SEQUENCE. RA Nowell W R.; RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:CAF4438142.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAJOBG010044681; CAF4438142.1; -; Genomic_DNA. DR AlphaFoldDB; A0A820RI30; -. DR Proteomes; UP000663866; Unassembled WGS sequence. DR GO; GO:0007267; P:cell-cell signaling; IEA:InterPro. DR GO; GO:0016540; P:protein autoprocessing; IEA:InterPro. DR InterPro; IPR000742; EGF-like_dom. DR InterPro; IPR001657; Hedgehog. DR InterPro; IPR001767; Hedgehog_Hint. DR InterPro; IPR003586; Hint_dom_C. DR InterPro; IPR003587; Hint_dom_N. DR InterPro; IPR036844; Hint_dom_sf. DR Pfam; PF01079; Hint; 1. DR PRINTS; PR00632; SONICHHOG. DR SMART; SM00181; EGF; 3. DR SMART; SM00305; HintC; 1. DR SMART; SM00306; HintN; 1. DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1. DR PROSITE; PS00022; EGF_1; 2. DR PROSITE; PS50026; EGF_3; 3. PE 4: Predicted; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473}; KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076}; KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076}; KW Reference proteome {ECO:0000313|Proteomes:UP000663866}; KW Signal {ECO:0000256|ARBA:ARBA00022729}. FT DOMAIN 1..24 FT /note="EGF-like" FT /evidence="ECO:0000259|PROSITE:PS50026" FT DOMAIN 61..99 FT /note="EGF-like" FT /evidence="ECO:0000259|PROSITE:PS50026" FT DOMAIN 100..136 FT /note="EGF-like" FT /evidence="ECO:0000259|PROSITE:PS50026" FT DISULFID 14..23 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076" FT DISULFID 70..87 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076" FT DISULFID 89..98 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076" FT DISULFID 126..135 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076" FT NON_TER 336 FT /evidence="ECO:0000313|EMBL:CAF4438142.1" SQ SEQUENCE 336 AA; 37158 MW; 758481E7B28D3688 CRC64; TCVLLENNQA QCLCTPVFRG LTCNQFSYVP CGDATCHGTQ GHCVANSCIC KTGFAGPRCD STDFCATFPC LNGGTCVRTN EEPYGGCSCP AEFSGPTCSN DPCSPSPCLN GGYCVRKADN QFYCQCRNRN KGVYCEQVEC FPSDATVDVL NIGKVPLSSL QIGSQVRIIN EEDQVSYSPI IAFLHRELDG QALYKRVRTR SSTIELSSRH LINQRKDGFV WAETLNKGDE IRVLLSTHAN ETQWEEVVEI TDVHKQGLMA PLTEQGTIVV NNVHASCYAL VKSHKVAHFA LAPYRLYHRL FGQLSDTDLM TKPILSYAST LLHFFKNLPI AKDLIF //