ID A0A811YIZ1_NYCPR Unreviewed; 609 AA. AC A0A811YIZ1; DT 29-SEP-2021, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 1. DT 25-MAY-2022, entry version 3. DE SubName: Full=(raccoon dog) hypothetical protein {ECO:0000313|EMBL:CAD7676864.1}; GN ORFNames=NYPRO_LOCUS9659 {ECO:0000313|EMBL:CAD7676864.1}; OS Nyctereutes procyonoides (Raccoon dog) (Canis procyonoides). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Nyctereutes. OX NCBI_TaxID=34880 {ECO:0000313|EMBL:CAD7676864.1, ECO:0000313|Proteomes:UP000645828}; RN [1] {ECO:0000313|EMBL:CAD7676864.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TBG_1078 {ECO:0000313|EMBL:CAD7676864.1}; RG Molecular Ecology Group; RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:CAD7676864.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAJHUB010000678; CAD7676864.1; -; Genomic_DNA. DR Proteomes; UP000645828; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IEA:InterPro. DR GO; GO:0045824; P:negative regulation of innate immune response; IEA:InterPro. DR GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:InterPro. DR CDD; cd08796; Death_IRAK-M; 1. DR CDD; cd14160; PK_IRAK3; 1. DR Gene3D; 1.10.533.10; -; 1. DR InterPro; IPR011029; DEATH-like_dom_sf. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR033610; IRAK3. DR InterPro; IPR042747; IRAK3_death. DR InterPro; IPR042698; IRAK3_PK. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR PANTHER; PTHR24419:SF7; PTHR24419:SF7; 1. DR Pfam; PF00531; Death; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00005; DEATH; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS50017; DEATH_DOMAIN; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000645828}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..27 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 28..609 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5032726505" FT DOMAIN 43..108 FT /note="Death" FT /evidence="ECO:0000259|PROSITE:PS50017" FT DOMAIN 167..454 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT REGION 522..578 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 532..547 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 609 AA; 68558 MW; 6E8AC754464FF19A CRC64; MAWAAGGGAR GALSAHTLLF DLPPALLGEL CAVLDSCDGA LGWRGLAERL SSSWLDVRHI EKYVDQGKSG TRELLWSWAQ KNKTIGDLLQ ILQEMGHHRA IHLIVNYGTA LNPSEQSHQR DGFPNMLPKE TANVTTDNVL TPKHNEKGIL FKSSISFQNI RDGTKNFHKD FLIGEGEIFE VYRAEIQNRT YAIKLFKQEK KMQCKKQWKR FLSELEVLLL FHHPNILELA AYFTENEKFC LVYPYMRNGS LSDRLQCVGN TAPLSWHIRI SVLLGTARAI QYLHNTEPCS VICGSVSSAN ILLDDQFQPK LTDFGMAHFR PHLEHQSCTI SVASSSSKHL WYMPEEYIRQ GKLSIKTDVY SFGIVIMEVL TGCKVVLDDP KHIQLRDLLM ELMEKRGLDS CLSFLDKKVH PCPRNFSAKL FSLAGQCATS RAKLRPSMDE VLTTLESTQA SLYFAEDPPT SLKSFRCPSP LFLENVPSIP VEDDENQNNH SLPHDKGLRK VGVTQKVPFE CSQSEVTFLG FDRKTGSERN EDTCNRPSSS CKESGSPKHV ALSQDPGAYG TDMDPSVEAP GHSYRSRPVE TSCSCEFSWN ECEQYKRESI SPDDKEESK //