ID A0A7U9PK73_MYCTX Unreviewed; 225 AA. AC A0A7U9PK73; DT 02-JUN-2021, integrated into UniProtKB/TrEMBL. DT 02-JUN-2021, sequence version 1. DT 19-JAN-2022, entry version 3. DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:GAA45281.1}; GN ORFNames=NCGM2209_1904 {ECO:0000313|EMBL:GAA45281.1}; OS Mycobacterium tuberculosis NCGM2209. OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; OC Mycobacterium; Mycobacterium tuberculosis complex. OX NCBI_TaxID=1078763 {ECO:0000313|EMBL:GAA45281.1}; RN [1] {ECO:0000313|EMBL:GAA45281.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCGM2209 {ECO:0000313|EMBL:GAA45281.1}; RX PubMed=22072647; DOI=10.1128/JB.06233-11; RA Miyoshi-Akiyama T., Matsumura K., Kobayashi N., Maeda S., Kirikae T.; RT "Genome Sequence of Clinical Isolate Mycobacterium tuberculosis NCGM2209."; RL J. Bacteriol. 193:6792-6792(2011). RN [2] {ECO:0000313|EMBL:GAA45281.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=NCGM2209 {ECO:0000313|EMBL:GAA45281.1}; RA Akiyama T., Matsumura K., Kirikae T.; RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DF126614; GAA45281.1; -; Genomic_DNA. DR RefSeq; WP_003407700.1; NZ_DF126614.1. DR SMR; A0A7U9PK73; -. DR GeneID; 45425517; -. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS. DR InterPro; IPR009057; Homeobox-like_sf. DR InterPro; IPR001647; HTH_TetR. DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf. DR Pfam; PF00440; TetR_N; 1. DR PRINTS; PR00455; HTHTETR. DR SUPFAM; SSF46689; SSF46689; 1. DR SUPFAM; SSF48498; SSF48498; 1. DR PROSITE; PS01081; HTH_TETR_1; 1. DR PROSITE; PS50977; HTH_TETR_2; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 18..78 FT /note="HTH tetR-type" FT /evidence="ECO:0000259|PROSITE:PS50977" FT DNA_BIND 41..60 FT /note="H-T-H motif" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335" SQ SEQUENCE 225 AA; 24501 MW; 9D73F0F47ED67DDD CRC64; MSRASARRRR AVSDEDKSQR RDEILAAAKI VFAHKGFHAT TVADIAKQAG LAYGLIYWYF DSKDDLFHAL MAGEEEALRA HVAAELARVG GSTEAPLRAL LQAAVQATFE FFETDKATVK LLFRDAYALG GRFEEHLGGI YERFIDDIEA VVVAAQRRGE VVEAPSRMAA YTLAALVGQL AHRRLNTDDN VTAAQVADFV VSLVLDGLRP RALAVGARGG RAART //