ID A0A7U9B8Z9_ECOLX Unreviewed; 210 AA. AC A0A7U9B8Z9; DT 02-JUN-2021, integrated into UniProtKB/TrEMBL. DT 02-JUN-2021, sequence version 1. DT 19-JAN-2022, entry version 3. DE RecName: Full=Catabolite activator protein {ECO:0000256|ARBA:ARBA00019336}; DE AltName: Full=Catabolite gene activator {ECO:0000256|ARBA:ARBA00022100}; DE AltName: Full=cAMP receptor protein {ECO:0000256|ARBA:ARBA00015410}; DE AltName: Full=cAMP regulatory protein {ECO:0000256|ARBA:ARBA00017259}; DE AltName: Full=cAMP-activated global transcriptional regulator CRP {ECO:0000256|ARBA:ARBA00015905}; GN ORFNames=ECLG_01714 {ECO:0000313|EMBL:EGI34156.1}; OS Escherichia coli TA271. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=656443 {ECO:0000313|EMBL:EGI34156.1, ECO:0000313|Proteomes:UP000004645}; RN [1] {ECO:0000313|EMBL:EGI34156.1, ECO:0000313|Proteomes:UP000004645} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TA271 {ECO:0000313|EMBL:EGI34156.1, RC ECO:0000313|Proteomes:UP000004645}; RG The Broad Institute Genome Sequencing Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q., RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D., RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J., RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.; RT "The Genome Sequence of Escherichia coli TA271."; RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GL884291; EGI34156.1; -; Genomic_DNA. DR SMR; A0A7U9B8Z9; -. DR Proteomes; UP000004645; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR CDD; cd00038; CAP_ED; 1. DR Gene3D; 1.10.10.10; -; 1. DR Gene3D; 2.60.120.10; -; 1. DR InterPro; IPR018490; cNMP-bd-like. DR InterPro; IPR018488; cNMP-bd_CS. DR InterPro; IPR000595; cNMP-bd_dom. DR InterPro; IPR012318; HTH_CRP. DR InterPro; IPR014710; RmlC-like_jellyroll. DR InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR Pfam; PF00027; cNMP_binding; 1. DR Pfam; PF13545; HTH_Crp_2; 1. DR PRINTS; PR00034; HTHCRP. DR SMART; SM00100; cNMP; 1. DR SMART; SM00419; HTH_CRP; 1. DR SUPFAM; SSF46785; SSF46785; 1. DR SUPFAM; SSF51206; SSF51206; 1. DR PROSITE; PS00888; CNMP_BINDING_1; 1. DR PROSITE; PS00889; CNMP_BINDING_2; 1. DR PROSITE; PS50042; CNMP_BINDING_3; 1. DR PROSITE; PS00042; HTH_CRP_1; 1. DR PROSITE; PS51063; HTH_CRP_2; 1. PE 4: Predicted; KW Acetylation {ECO:0000256|ARBA:ARBA00022990}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}. FT DOMAIN 24..124 FT /note="Cyclic nucleotide-binding" FT /evidence="ECO:0000259|PROSITE:PS50042" FT DOMAIN 138..210 FT /note="HTH crp-type" FT /evidence="ECO:0000259|PROSITE:PS51063" SQ SEQUENCE 210 AA; 23640 MW; DCBC24FA46C61B3D CRC64; MVLGKPQTDP TLEWFLSHCH IHKYPSKSTL IHQGEKAETL YYIVKGSVAV LIKDEEGKEM ILSYLNQGDF IGELGLFEEG QERSAWVRAK TACEVAEISY KKFRQLIQVN PDILMRLSAQ MARRLQVTSE KVGNLAFLDV TGRIAQTLLN LAKQPDAMTH PDGMQIKITR QEIGQIVGCS RETVGRILKM LEDQNLISAH GKTIVVYGTR //