ID A0A7N9CC80_MACFA Unreviewed; 527 AA. AC A0A7N9CC80; DT 02-JUN-2021, integrated into UniProtKB/TrEMBL. DT 02-JUN-2021, sequence version 1. DT 19-JAN-2022, entry version 3. DE SubName: Full=Aldehyde dehydrogenase 1 family member A1 {ECO:0000313|Ensembl:ENSMFAP00000048002}; OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000048002, ECO:0000313|Proteomes:UP000233100}; RN [1] {ECO:0000313|Ensembl:ENSMFAP00000048002, ECO:0000313|Proteomes:UP000233100} RP NUCLEOTIDE SEQUENCE. RA Warren W., Wilson R.K.; RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSMFAP00000048002} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2021) to UniProtKB. CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family. CC {ECO:0000256|RuleBase:RU003345}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSMFAT00000094010; ENSMFAP00000048002; ENSMFAG00000038785. DR GeneTree; ENSGT00940000154609; -. DR Proteomes; UP000233100; Chromosome 15. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0106373; F:3-deoxyglucosone dehydrogenase activity; IEA:Ensembl. DR GO; GO:0110095; P:cellular detoxification of aldehyde; IEA:Ensembl. DR GO; GO:0030392; P:fructosamine catabolic process; IEA:Ensembl. DR Gene3D; 3.40.309.10; -; 1. DR Gene3D; 3.40.605.10; -; 1. DR InterPro; IPR016161; Ald_DH/histidinol_DH. DR InterPro; IPR016163; Ald_DH_C. DR InterPro; IPR016160; Ald_DH_CS_CYS. DR InterPro; IPR029510; Ald_DH_CS_GLU. DR InterPro; IPR016162; Ald_DH_N. DR InterPro; IPR015590; Aldehyde_DH_dom. DR Pfam; PF00171; Aldedh; 1. DR SUPFAM; SSF53720; SSF53720; 1. DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1. DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1. PE 3: Inferred from homology; KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, KW ECO:0000256|RuleBase:RU003345}; KW Reference proteome {ECO:0000313|Proteomes:UP000233100}. FT DOMAIN 55..518 FT /note="Aldedh" FT /evidence="ECO:0000259|Pfam:PF00171" FT REGION 1..37 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..34 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT ACT_SITE 295 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007" FT ACT_SITE 329 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10008" SQ SEQUENCE 527 AA; 57878 MW; ABEC5528C68AF4CA CRC64; MPDRGKGDMC LVEKRRWEGR NGADDQDGKR DLQTPREPTT CSFTALQEIF INNEWHDSVS GKKFPVFNPA TEEELCQVEE GDKADVDKAV KAARQAFQIG SPWRTMDASE RGRLLYKLAD LIERDRLLLA TMESMNGGKL YSNAYLNDLA GCIKTLRYCA GWADKIQGRT IPIDGNFFTY TRHEPIGVCG QIIPWNFPLV MLIWKIGPAL SCGNTVVVKP AEQTPLTALH VASLIKEAGF PPGVVNIVPG YGPTAGAAIS SHMDIDKVAF TGSTEVGKLI KEAAGKSNLK RVTLELGGKS PCIVLADADL DNAVEFAHHG VFYHQGQCCI AASRIFVEES IYDEFVRRSV ERAKKYILGN PLTPGVTQGP QIDKEQYDKI LDLIESGKKE GAKLECGGGP WGNKGYFVQP TVFSNVTDEM RIAKEEIFGP VQQIMKFKSL DDVIKRANNT FYGLSAGVFT NDIDKAVTIS SALQAGTVWV NCYGVVTAQC PFGGFKMSGN GRELGEYGFH EYTEVKTVTV KISQKNS //