ID A0A7K4GQG8_9ARCH Unreviewed; 636 AA. AC A0A7K4GQG8; DT 07-APR-2021, integrated into UniProtKB/TrEMBL. DT 07-APR-2021, sequence version 1. DT 03-MAY-2023, entry version 6. DE SubName: Full=Beta-CASP ribonuclease aCPSF1 {ECO:0000313|EMBL:NVM18131.1}; GN ORFNames=HWN80_10470 {ECO:0000313|EMBL:NVM18131.1}; OS Candidatus Lokiarchaeota archaeon. OC Archaea; Asgard group; Candidatus Lokiarchaeota. OX NCBI_TaxID=2053489 {ECO:0000313|EMBL:NVM18131.1, ECO:0000313|Proteomes:UP000538462}; RN [1] {ECO:0000313|EMBL:NVM18131.1, ECO:0000313|Proteomes:UP000538462} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hel_238_bin90 {ECO:0000313|EMBL:NVM18131.1}; RA Yin X.; RT "Subgroup level differences of physiological activities in marine RT Lokiarchaeota."; RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:NVM18131.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JABXKC010000014; NVM18131.1; -; Genomic_DNA. DR AlphaFoldDB; A0A7K4GQG8; -. DR Proteomes; UP000538462; Unassembled WGS sequence. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR CDD; cd22532; KH-II_CPSF_arch_rpt1; 1. DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1. DR Gene3D; 3.30.300.20; -; 1. DR Gene3D; 3.30.300.230; -; 1. DR Gene3D; 3.40.50.10890; -; 1. DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1. DR InterPro; IPR019975; aCPSF1. DR InterPro; IPR022712; Beta_Casp. DR InterPro; IPR033769; KH_arc. DR InterPro; IPR015946; KH_dom-like_a/b. DR InterPro; IPR004044; KH_dom_type_2. DR InterPro; IPR009019; KH_sf_prok-type. DR InterPro; IPR001279; Metallo-B-lactamas. DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro. DR InterPro; IPR011108; RMMBL. DR PANTHER; PTHR11203:SF51; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; 1. DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1. DR Pfam; PF10996; Beta-Casp; 1. DR Pfam; PF07650; KH_2; 1. DR Pfam; PF17214; KH_7; 1. DR Pfam; PF16661; Lactamase_B_6; 1. DR Pfam; PF07521; RMMBL; 1. DR SMART; SM01027; Beta-Casp; 1. DR SMART; SM00849; Lactamase_B; 1. DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1. DR SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 1. DR TIGRFAMs; TIGR03675; arCOG00543; 1. PE 4: Predicted; KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}. FT DOMAIN 194..409 FT /note="Metallo-beta-lactamase" FT /evidence="ECO:0000259|SMART:SM00849" FT DOMAIN 421..545 FT /note="Beta-Casp" FT /evidence="ECO:0000259|SMART:SM01027" SQ SEQUENCE 636 AA; 71956 MW; D2C1FBED9F5A7BEC CRC64; MSFEGELQRI KEEIIKYLPP EIEVKKIEFE GPEIAVYSEN TNLESIESTE ILKDLAKSMR KRVVFRWNVE KRKDPSETED YIRNLISEDA EISEIEFDHT RGEVIIESGK PGLVIGKKGV NLKEIRMNTF WQPKTIRTPP LASRTISLIR QMLTKERQNQ KDILLNIGKR IHRPALFNDL DIRLTSLGGF REVGRSCILM QTRDSNVLLD VGLNVGNKND QFPHFDVPEF SVRDLDAVII SHAHLDHCGM VPYLFKYGYR GPVYCTLPTR NLSTMLQLDF VQICEKEGVP MPYSKRDVKN AVLHTIPLSW GKVTDIAPDI KLTLHNSGHI LGSSLVHLHF GKGGFNFIYT GDMKYQKTRL LEKAAVKFPR VEALLVESTY GGPQDRIPSR QDSERELRQI LTSTIRRGGK VLIPVLAVGR AQELIIVLEE LISKAIIDQV PIFLDGLISE ATAIHTANPD FLSSDLREKI LHQGKNPFLS EFFTTVSGHD ERNDVIMGGP CIILATSGML IGGPSVQYLK ALAEDKNNSL IFVSYQVNGT LGSRIQRGFR EIQYTNAKGR TQLVRLNLNV FTLEGFSGHS SRSQISQFLR RIQPKPKLVI TNHGEESKCV SLSTMIHKKL RKATKSPKNR ETILLK //