ID A0A7J9M7S5_GOSSC Unreviewed; 370 AA. AC A0A7J9M7S5; DT 07-APR-2021, integrated into UniProtKB/TrEMBL. DT 07-APR-2021, sequence version 1. DT 27-MAR-2024, entry version 8. DE RecName: Full=laccase {ECO:0000256|ARBA:ARBA00012297}; DE EC=1.10.3.2 {ECO:0000256|ARBA:ARBA00012297}; DE Flags: Fragment; GN ORFNames=Goshw_027956 {ECO:0000313|EMBL:MBA0867172.1}; OS Gossypium schwendimanii (Cotton). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium. OX NCBI_TaxID=34291 {ECO:0000313|EMBL:MBA0867172.1, ECO:0000313|Proteomes:UP000593576}; RN [1] {ECO:0000313|EMBL:MBA0867172.1, ECO:0000313|Proteomes:UP000593576} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1 {ECO:0000313|EMBL:MBA0867172.1}; RC TISSUE=Leaf {ECO:0000313|EMBL:MBA0867172.1}; RX PubMed=30476109; RA Grover C.E., Arick M.A. 2nd, Thrash A., Conover J.L., Sanders W.S., RA Peterson D.G., Frelichowski J.E., Scheffler J.A., Scheffler B.E., RA Wendel J.F.; RT "Insights into the Evolution of the New World Diploid Cottons (Gossypium, RT Subgenus Houzingenia) Based on Genome Sequencing."; RL Genome Biol. Evol. 11:53-71(2019). CC -!- CATALYTIC ACTIVITY: CC Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; CC Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, CC ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; CC Evidence={ECO:0000256|ARBA:ARBA00000349}; CC -!- COFACTOR: CC Name=Cu cation; Xref=ChEBI:CHEBI:23378; CC Evidence={ECO:0000256|ARBA:ARBA00001935}; CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast CC {ECO:0000256|ARBA:ARBA00004271}. CC -!- SIMILARITY: Belongs to the multicopper oxidase family. CC {ECO:0000256|ARBA:ARBA00010609}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:MBA0867172.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JABFAF010000009; MBA0867172.1; -; Genomic_DNA. DR AlphaFoldDB; A0A7J9M7S5; -. DR Proteomes; UP000593576; Unassembled WGS sequence. DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell. DR GO; GO:0005507; F:copper ion binding; IEA:InterPro. DR GO; GO:0052716; F:hydroquinone:oxygen oxidoreductase activity; IEA:UniProtKB-EC. DR GO; GO:0046274; P:lignin catabolic process; IEA:UniProtKB-KW. DR CDD; cd13875; CuRO_2_LCC_plant; 1. DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 3. DR InterPro; IPR011707; Cu-oxidase-like_N. DR InterPro; IPR001117; Cu-oxidase_2nd. DR InterPro; IPR011706; Cu-oxidase_C. DR InterPro; IPR045087; Cu-oxidase_fam. DR InterPro; IPR033138; Cu_oxidase_CS. DR InterPro; IPR002355; Cu_oxidase_Cu_BS. DR InterPro; IPR008972; Cupredoxin. DR InterPro; IPR034285; CuRO_2_LCC. DR PANTHER; PTHR11709:SF431; LACCASE-12; 1. DR PANTHER; PTHR11709; MULTI-COPPER OXIDASE; 1. DR Pfam; PF00394; Cu-oxidase; 1. DR Pfam; PF07731; Cu-oxidase_2; 1. DR Pfam; PF07732; Cu-oxidase_3; 1. DR SUPFAM; SSF49503; Cupredoxins; 3. DR PROSITE; PS00079; MULTICOPPER_OXIDASE1; 1. DR PROSITE; PS00080; MULTICOPPER_OXIDASE2; 1. PE 3: Inferred from homology; KW Apoplast {ECO:0000256|ARBA:ARBA00022523}; KW Copper {ECO:0000256|ARBA:ARBA00023008}; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Lignin degradation {ECO:0000256|ARBA:ARBA00023185}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}; KW Reference proteome {ECO:0000313|Proteomes:UP000593576}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}. FT DOMAIN 1..51 FT /note="Plastocyanin-like" FT /evidence="ECO:0000259|Pfam:PF07732" FT DOMAIN 65..214 FT /note="Plastocyanin-like" FT /evidence="ECO:0000259|Pfam:PF00394" FT DOMAIN 286..352 FT /note="Plastocyanin-like" FT /evidence="ECO:0000259|Pfam:PF07731" FT NON_TER 370 FT /evidence="ECO:0000313|EMBL:MBA0867172.1" SQ SEQUENCE 370 AA; 40589 MW; 33D58D7B385DE1A7 CRC64; GPEFVTQCPI RPGGSYTYRF TIQGQEGTLW WHAHSSWLRA TVYGALIIRP RLGESYPFPK PNLETPIVLG EWWDANPIDV VREATRTGAA PNVSDACTIN AQPGDLYKCS SKDTTSIPID AGETNLLRVI NAALNQPLFF SVANHTLTVV GADATYIKPF TTSVLMLGAG QTTDVLIKAD QRPARYYMAA RAYQSAQNVP FDSTTTTAIL EYKSSKKGNA PKLIMPSLPA YNDTNTVTAF SRSFRSPQKV QVPTEIDESL FFTVGLGLNN CPPNFRRSRC QGPNEGFGNF NPKRDTSKFN LVDPPLRNMV AVPANGWAVI RFVADNPGVW LMHCHLDVHI TWGLAMAFLV ENGVGELQSL PAPPSDLPLC //