ID A0A7J8AHM0_MYOMY Unreviewed; 489 AA. AC A0A7J8AHM0; DT 07-APR-2021, integrated into UniProtKB/TrEMBL. DT 07-APR-2021, sequence version 1. DT 03-AUG-2022, entry version 4. DE SubName: Full=Bardet-Biedl syndrome 4 {ECO:0000313|EMBL:KAF6386097.1}; GN ORFNames=mMyoMyo1_001383 {ECO:0000313|EMBL:KAF6386097.1}; OS Myotis myotis (Greater mouse-eared bat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae; OC Myotis. OX NCBI_TaxID=51298 {ECO:0000313|EMBL:KAF6386097.1, ECO:0000313|Proteomes:UP000527355}; RN [1] {ECO:0000313|EMBL:KAF6386097.1, ECO:0000313|Proteomes:UP000527355} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MMyoMyo1 {ECO:0000313|EMBL:KAF6386097.1}; RC TISSUE=Flight muscle {ECO:0000313|EMBL:KAF6386097.1}; RX PubMed=32699395; RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P., RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L., RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M., RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N., RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M., RA Vernes S.C., Myers E.W., Teeling E.C.; RT "Six reference-quality genomes reveal evolution of bat adaptations."; RL Nature 583:578-584(2020). CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Membrane CC {ECO:0000256|ARBA:ARBA00004370}. CC -!- SIMILARITY: Belongs to the BBS4 family. CC {ECO:0000256|ARBA:ARBA00023778}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAF6386097.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JABWUV010000001; KAF6386097.1; -; Genomic_DNA. DR Proteomes; UP000527355; Unassembled WGS sequence. DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. DR Gene3D; 1.25.40.10; -; 2. DR InterPro; IPR028786; BBS4. DR InterPro; IPR011990; TPR-like_helical_dom_sf. DR InterPro; IPR019734; TPR_repeat. DR PANTHER; PTHR44186; PTHR44186; 1. DR Pfam; PF13181; TPR_8; 2. DR SMART; SM00028; TPR; 8. DR SUPFAM; SSF48452; SSF48452; 1. DR PROSITE; PS50005; TPR; 4. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000527355}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE- KW ProRule:PRU00339}. FT REPEAT 168..201 FT /note="TPR" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339" FT REPEAT 202..235 FT /note="TPR" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339" FT REPEAT 304..337 FT /note="TPR" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339" FT REPEAT 338..371 FT /note="TPR" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339" FT REGION 1..23 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 439..489 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 449..477 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 489 AA; 55253 MW; 1CBFECAEC2F3EBCE CRC64; MAEERQPTRT QFPASAESQK PHLKKAPEFP ILEKQNWLIH LHYIRKDYEA CKAVIKEQLQ ETQGLCEYAI YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA TEVYNEAAKL NQKDWEIYHN LGVCYIYLKQ FNKAQDQLHH ALHLNRHDLT YIMLGKIHLL AGDLDKAIEI YKKAVEFSPE NTELLTTLGL LYLQVGIYQK AFEHLGNALT YDPVNYKAIL AAGSMMQTHG DFDVALTKYR VIASAVPESP PLWNNIGMCF FGKKKYVAAI SCLKRANYLA PFDWKILYNL GLVHLTMQQY ASAFHFLSAA INFQPKMGEL YMLLAVALTN LEDTENAKRA YAEAVRLDKY NPLVNLNYAV LLYNQGEKRD ALAQYQEMEK KVNLLKDSSS LEYDSEMVET AQKLGAALQV GEALVWTKPV KDPKSKQRTT STSKAASFQQ PLGSNQALGQ AMSSAAAYSK LPSGRRGHK //