ID A0A7J7EPA2_DICBM Unreviewed; 239 AA. AC A0A7J7EPA2; DT 07-APR-2021, integrated into UniProtKB/TrEMBL. DT 07-APR-2021, sequence version 1. DT 29-SEP-2021, entry version 3. DE RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363014}; DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU363014}; GN ORFNames=HPG69_017419 {ECO:0000313|EMBL:KAF5917527.1}; OS Diceros bicornis minor (South-central black rhinoceros). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Perissodactyla; Rhinocerotidae; Diceros. OX NCBI_TaxID=77932 {ECO:0000313|EMBL:KAF5917527.1, ECO:0000313|Proteomes:UP000551758}; RN [1] {ECO:0000313|EMBL:KAF5917527.1, ECO:0000313|Proteomes:UP000551758} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SBR-YM {ECO:0000313|EMBL:KAF5917527.1}; RC TISSUE=Skin {ECO:0000313|EMBL:KAF5917527.1}; RX PubMed=32585004; RA Moodley Y., Westbury M.V., Russo I.M., Gopalakrishnan S., Rakotoarivelo A., RA Olsen R.A., Prost S., Tunstall T., Ryder O.A., Dalen L., Bruford M.W.; RT "Interspecific Gene Flow and the Evolution of Specialization in Black and RT White Rhinoceros."; RL Mol. Biol. Evol. 37:3105-3117(2020). CC -!- CATALYTIC ACTIVITY: CC Reaction=[protein]-peptidylproline (omega=180) = [protein]- CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA- CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833, CC ChEBI:CHEBI:83834; EC=5.2.1.8; CC Evidence={ECO:0000256|ARBA:ARBA00000971, CC ECO:0000256|RuleBase:RU363014}; CC -!- SIMILARITY: Belongs to the PpiC/parvulin rotamase family. PIN4 CC subfamily. {ECO:0000256|ARBA:ARBA00010242}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAF5917527.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JACDTQ010002544; KAF5917527.1; -; Genomic_DNA. DR Proteomes; UP000551758; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-UniRule. DR GO; GO:0006364; P:rRNA processing; IEA:InterPro. DR InterPro; IPR043323; PIN4. DR InterPro; IPR000297; PPIase_PpiC. DR PANTHER; PTHR45995; PTHR45995; 1. DR PROSITE; PS50198; PPIC_PPIASE_2; 1. PE 3: Inferred from homology; KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00278, KW ECO:0000256|RuleBase:RU363014}; KW Reference proteome {ECO:0000313|Proteomes:UP000551758}; KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00278, KW ECO:0000256|RuleBase:RU363014}. FT DOMAIN 1..62 FT /note="PpiC" FT /evidence="ECO:0000259|PROSITE:PS50198" FT REGION 113..239 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 189..208 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 239 AA; 26559 MW; 71B39EB293C47727 CRC64; MEAMEKLKSG MRFNEVAAQY SEDKARQGGD LGWMTRGSMV GPFQEAAFAL PISGLDKPVF TDPPDDQKSP RWRQRRFEPR LRSRIRAYIC AAGLLYPSGT RFPLRLAQRP RGQSGEALAS STAAATPWPA HHRRSPSYLR PSDHHLHLTP PSIPAKYPRS LSNVEAKRRT GKPWTAGRIY LTSQGPKLRS IPREEHSESF RQEGGERRGL DPVSAGAERQ GRRRAGGGAS PLTLGRRGV //