ID A0A7I2V3M8_HUMAN Unreviewed; 37 AA. AC A0A7I2V3M8; DT 07-APR-2021, integrated into UniProtKB/TrEMBL. DT 07-APR-2021, sequence version 1. DT 29-MAY-2024, entry version 13. DE SubName: Full=Glycogen synthase kinase 3 alpha {ECO:0000313|Ensembl:ENSP00000503594.1}; DE Flags: Fragment; GN Name=GSK3A {ECO:0000313|Ensembl:ENSP00000503594.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000503594.1, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000503594.1, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15057824; DOI=10.1038/nature02399; RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A., RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., RA Rubin E.M., Lucas S.M.; RT "The DNA sequence and biology of human chromosome 19."; RL Nature 428:529-535(2004). RN [2] {ECO:0000313|Ensembl:ENSP00000503594.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC006486; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KC877743; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF456580; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PeptideAtlas; A0A7I2V3M8; -. DR Ensembl; ENST00000676517.1; ENSP00000503594.1; ENSG00000105723.13. DR HGNC; HGNC:4616; GSK3A. DR GeneTree; ENSGT00520000055635; -. DR Proteomes; UP000005640; Chromosome 19. DR Bgee; ENSG00000105723; Expressed in cortical plate and 213 other cell types or tissues. DR GO; GO:0030424; C:axon; IEA:TreeGrafter. DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter. DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:TreeGrafter. DR GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:TreeGrafter. DR GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:TreeGrafter. DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:TreeGrafter. DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:TreeGrafter. DR GO; GO:0010975; P:regulation of neuron projection development; IEA:TreeGrafter. DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1. DR InterPro; IPR011009; Kinase-like_dom_sf. DR PANTHER; PTHR24057; GLYCOGEN SYNTHASE KINASE-3 ALPHA; 1. DR PANTHER; PTHR24057:SF0; PROTEIN KINASE SHAGGY-RELATED; 1. DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSP00000503594.1" SQ SEQUENCE 37 AA; 4152 MW; 029F21008A8E0218 CRC64; XAKQLVRGEP NVSYICSRYY RAPELIFGAT DYTSSIA //