ID A0A7G7FZ83_9BACI Unreviewed; 426 AA. AC A0A7G7FZ83; DT 10-FEB-2021, integrated into UniProtKB/TrEMBL. DT 10-FEB-2021, sequence version 1. DT 24-JAN-2024, entry version 8. DE RecName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040619}; GN ORFNames=HUW50_23800 {ECO:0000313|EMBL:QNF30217.1}; OS Metabacillus sp. KUDC1714. OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Metabacillus. OX NCBI_TaxID=2745198 {ECO:0000313|EMBL:QNF30217.1, ECO:0000313|Proteomes:UP000515490}; RN [1] {ECO:0000313|EMBL:QNF30217.1, ECO:0000313|Proteomes:UP000515490} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KUDC1714 {ECO:0000313|EMBL:QNF30217.1, RC ECO:0000313|Proteomes:UP000515490}; RA Lee S.Y., Hwang Y.J., Son J.S., Ghim S.Y.; RT "Metabacillus dokdonensis sp. nov., isolated from the rhizosphere of Elymus RT tsukushiensis, a plant native to the Dokdo Islands, Republic of Korea."; RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Lysosome CC membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004155}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP055263; QNF30217.1; -; Genomic_DNA. DR RefSeq; WP_066339270.1; NZ_CP055263.1. DR AlphaFoldDB; A0A7G7FZ83; -. DR KEGG; meku:HUW50_23800; -. DR Proteomes; UP000515490; Chromosome. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro. DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2. DR InterPro; IPR011701; MFS. DR InterPro; IPR020846; MFS_dom. DR InterPro; IPR036259; MFS_trans_sf. DR PANTHER; PTHR23512; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1; 1. DR PANTHER; PTHR23512:SF3; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1; 1. DR Pfam; PF07690; MFS_1; 1. DR SUPFAM; SSF103473; MFS general substrate transporter; 1. DR PROSITE; PS50850; MFS; 1. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 7..23 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 43..62 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 74..95 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 101..124 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 136..160 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 166..186 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 227..251 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 263..282 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 294..313 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 319..343 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 352..370 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 390..411 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 12..416 FT /note="Major facilitator superfamily (MFS) profile" FT /evidence="ECO:0000259|PROSITE:PS50850" SQ SEQUENCE 426 AA; 46775 MW; 35AF87D91CC4368A CRC64; MDKQNSKFRW IVFATVLFTY FIIVSQRTAP GLISDQLMKD FNVTASTIGL LASIQFFAYA GLQVPIGILS DRFGPNLFLI VGTLLTGVGT LLYSLAPNES ILFLARLIVG TGDATIWVNV VLILSQWFKG NEFIKLLGMA GMTGSLGFLM ATVPFSIWIA LSGWRASFFT MGIILCLCGI LLYFVLVKYP KRMVKNNAIT SSSSVKSEHK REKTLVILNR IFSNQQAWAA FLCHFGAVGT YVGFIGSWAV PYGMDIFDMT RSGASQFIMI GLIGALIGAP LTSWISSRMQ SIKIPYITVH LLIFLSWSAF LLFSGKPPLI ILMVLFLLIG YGNGASALTF AIVRQSFDVK EVGVASGFAN MGGFLSAVLL PSFFGKVLDH FQLAESNVGY LYGFMIPVIF SMIGLFGGFL IKEQHQEITQ TKELSV //