ID A0A7G2FB00_ARATH Unreviewed; 281 AA. AC A0A7G2FB00; DT 10-FEB-2021, integrated into UniProtKB/TrEMBL. DT 10-FEB-2021, sequence version 1. DT 29-SEP-2021, entry version 4. DE RecName: Full=Isopentenyl-diphosphate Delta-isomerase {ECO:0000256|ARBA:ARBA00012057}; DE EC=5.3.3.2 {ECO:0000256|ARBA:ARBA00012057}; GN ORFNames=AT9943_LOCUS19305 {ECO:0000313|EMBL:CAD5331860.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:CAD5331860.1, ECO:0000313|Proteomes:UP000516314}; RN [1] {ECO:0000313|EMBL:CAD5331860.1, ECO:0000313|Proteomes:UP000516314} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Cdm-0 {ECO:0000313|Proteomes:UP000516314}; RA Ashkenazy H.; RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the 1,3-allylic rearrangement of the homoallylic CC substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, CC dimethylallyl diphosphate (DMAPP). {ECO:0000256|ARBA:ARBA00003951}. CC -!- CATALYTIC ACTIVITY: CC Reaction=isopentenyl diphosphate = dimethylallyl diphosphate; CC Xref=Rhea:RHEA:23284, ChEBI:CHEBI:57623, ChEBI:CHEBI:128769; CC EC=5.3.3.2; Evidence={ECO:0000256|ARBA:ARBA00000374}; CC -!- PATHWAY: Isoprenoid biosynthesis; dimethylallyl diphosphate CC biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: CC step 1/1. {ECO:0000256|ARBA:ARBA00004826}. CC -!- PATHWAY: Porphyrin-containing compound metabolism; chlorophyll CC biosynthesis. {ECO:0000256|ARBA:ARBA00005173}. CC -!- SIMILARITY: Belongs to the IPP isomerase type 1 family. CC {ECO:0000256|ARBA:ARBA00007579}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LR881470; CAD5331860.1; -; Genomic_DNA. DR OMA; VEQEYNH; -. DR UniPathway; UPA00059; UER00104. DR UniPathway; UPA00668; -. DR Proteomes; UP000516314; Chromosome 5. DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro. DR GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IEA:UniProtKB-EC. DR GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. DR CDD; cd02885; IPP_Isomerase; 1. DR InterPro; IPR011876; IsopentenylPP_isomerase_typ1. DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf. DR InterPro; IPR000086; NUDIX_hydrolase_dom. DR Pfam; PF00293; NUDIX; 1. DR SUPFAM; SSF55811; SSF55811; 1. DR TIGRFAMs; TIGR02150; IPP_isom_1; 1. DR PROSITE; PS51462; NUDIX; 1. PE 3: Inferred from homology; KW Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171}; KW Isomerase {ECO:0000256|ARBA:ARBA00023235}; KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229}. FT DOMAIN 99..251 FT /note="Nudix hydrolase" FT /evidence="ECO:0000259|PROSITE:PS51462" FT REGION 20..43 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 20..35 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 281 AA; 32097 MW; F5ED3F74D2F07B6C CRC64; MSTASLFSFP SFHLRSLLPS LSSSSSSSSS RFAPPRLSPI RSPAPRTQLS VRAFSAVTMT DSNDAGMDAV QRRLMFEDEC ILVDENDRHL MEKIEAENLL HRAFSVFLFN SKYELLLQQR SKTKVTFPLV WTNTCCSHPL YRESELIEEN VLGVRNAAQR KLFDELGIVA EDVPVDEFTP LGRMLYKAPS DGKWGEHEVD YLLFIVRDVK LQPNPDEVAE IKYVSREELK ELVKKADAGD EAVKLSPWFR LVVDNFLMKW WDHVEKGTIT EAADMKTIHK L //