ID A0A7D9GX72_DEKBR Unreviewed; 89 AA. AC A0A7D9GX72; DT 10-FEB-2021, integrated into UniProtKB/TrEMBL. DT 10-FEB-2021, sequence version 1. DT 27-NOV-2024, entry version 12. DE RecName: Full=Protein transport protein Sec61 subunit beta {ECO:0000256|PIRNR:PIRNR006398}; GN Name=SBH2 {ECO:0000313|EMBL:VUG16003.1}; GN ORFNames=DEBR0S1_05094G {ECO:0000313|EMBL:VUG16003.1}, HII12_001784 GN {ECO:0000313|EMBL:KAF6013069.1}; OS Dekkera bruxellensis (Brettanomyces custersii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Pichiaceae; Brettanomyces. OX NCBI_TaxID=5007 {ECO:0000313|EMBL:VUG16003.1, ECO:0000313|Proteomes:UP000478008}; RN [1] {ECO:0000313|EMBL:VUG16003.1, ECO:0000313|Proteomes:UP000478008} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Friedrich A., Schacherer J.; RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:KAF6013069.1, ECO:0000313|Proteomes:UP000568158} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AWRI1613 {ECO:0000313|EMBL:KAF6013069.1, RC ECO:0000313|Proteomes:UP000568158}; RX PubMed=32592028; RA Varela C., Bartel C., Onetto C., Borneman A.; RT "Targeted gene deletion in Brettanomyces bruxellensis with an expression- RT free CRISPR-Cas9 system."; RL Appl. Microbiol. Biotechnol. 104:7105-7115(2020). CC -!- FUNCTION: Necessary for protein translocation in the endoplasmic CC reticulum. {ECO:0000256|PIRNR:PIRNR006398}. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004389}. CC -!- SIMILARITY: Belongs to the SEC61-beta family. CC {ECO:0000256|ARBA:ARBA00006103, ECO:0000256|PIRNR:PIRNR006398}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JABCYN010000022; KAF6013069.1; -; Genomic_DNA. DR EMBL; CABFWN010000001; VUG16003.1; -; Genomic_DNA. DR AlphaFoldDB; A0A7D9GX72; -. DR Proteomes; UP000478008; Unassembled WGS sequence. DR Proteomes; UP000568158; Unassembled WGS sequence. DR GO; GO:0005784; C:Sec61 translocon complex; IEA:UniProtKB-UniRule. DR GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IEA:TreeGrafter. DR GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IEA:TreeGrafter. DR InterPro; IPR030671; Sec61-beta/Sbh. DR InterPro; IPR016482; SecG/Sec61-beta/Sbh. DR PANTHER; PTHR13509:SF3; PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA; 1. DR PANTHER; PTHR13509; SEC61 SUBUNIT BETA; 1. DR Pfam; PF03911; Sec61_beta; 1. DR PIRSF; PIRSF006398; Sec61_beta_euk; 1. PE 3: Inferred from homology; KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824, KW ECO:0000256|PIRNR:PIRNR006398}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006398}; KW Protein transport {ECO:0000256|ARBA:ARBA00022927, KW ECO:0000256|PIRNR:PIRNR006398}; KW Reference proteome {ECO:0000313|Proteomes:UP000478008}; KW Translocation {ECO:0000256|ARBA:ARBA00023010, KW ECO:0000256|PIRNR:PIRNR006398}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006398}. FT TRANSMEM 62..81 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REGION 1..44 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 27..44 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 89 AA; 9538 MW; DC1CDBD6E4782F9D CRC64; MSSSIPGGAK TLSKRRANKE NKLRQQKLNK PNSSRAAGAG GSSSSMLKIY TDEADGFKID PLVVLIFAVA FIFSVVVLHV ISKLTGKIF //