ID A0A6V8S9P5_9CLOT Unreviewed; 279 AA. AC A0A6V8S9P5; DT 02-DEC-2020, integrated into UniProtKB/TrEMBL. DT 02-DEC-2020, sequence version 1. DT 19-JAN-2022, entry version 6. DE RecName: Full=Ribosomal RNA small subunit methyltransferase I {ECO:0000256|HAMAP-Rule:MF_01877}; DE EC=2.1.1.198 {ECO:0000256|HAMAP-Rule:MF_01877}; DE AltName: Full=16S rRNA 2'-O-ribose C1402 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877}; DE AltName: Full=rRNA (cytidine-2'-O-)-methyltransferase RsmI {ECO:0000256|HAMAP-Rule:MF_01877}; GN Name=rsmI {ECO:0000256|HAMAP-Rule:MF_01877}; GN ORFNames=bsdtw1_00021 {ECO:0000313|EMBL:GFP73984.1}; OS Clostridium fungisolvens. OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae; OC Clostridium. OX NCBI_TaxID=1604897 {ECO:0000313|EMBL:GFP73984.1, ECO:0000313|Proteomes:UP000580568}; RN [1] {ECO:0000313|EMBL:GFP73984.1, ECO:0000313|Proteomes:UP000580568} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TW1 {ECO:0000313|EMBL:GFP73984.1, RC ECO:0000313|Proteomes:UP000580568}; RA Ueki A., Tonouchi A.; RT "A new beta-1,3-glucan-decomposing anaerobic bacterium isolated from anoxic RT soil subjected to biological soil disinfestation."; RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 CC (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}. CC -!- CATALYTIC ACTIVITY: CC Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O- CC methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine; CC Xref=Rhea:RHEA:42924, Rhea:RHEA-COMP:10285, Rhea:RHEA-COMP:10286, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, CC ChEBI:CHEBI:74495, ChEBI:CHEBI:82748; EC=2.1.1.198; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01877}; CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877}. CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmI family. CC {ECO:0000256|HAMAP-Rule:MF_01877}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:GFP73984.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BLZR01000001; GFP73984.1; -; Genomic_DNA. DR Proteomes; UP000580568; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0070677; F:rRNA (cytosine-2'-O-)-methyltransferase activity; IEA:UniProtKB-UniRule. DR GO; GO:0000453; P:enzyme-directed rRNA 2'-O-methylation; IEA:UniProtKB-UniRule. DR CDD; cd11648; RsmI; 1. DR Gene3D; 3.30.950.10; -; 1. DR Gene3D; 3.40.1010.10; -; 1. DR HAMAP; MF_01877; 16SrRNA_methyltr_I; 1. DR InterPro; IPR000878; 4pyrrol_Mease. DR InterPro; IPR035996; 4pyrrol_Methylase_sf. DR InterPro; IPR014777; 4pyrrole_Mease_sub1. DR InterPro; IPR014776; 4pyrrole_Mease_sub2. DR InterPro; IPR008189; rRNA_ssu_MeTfrase_I. DR InterPro; IPR018063; SAM_MeTrfase_RsmI_CS. DR PANTHER; PTHR46111; PTHR46111; 1. DR Pfam; PF00590; TP_methylase; 1. DR PIRSF; PIRSF005917; MTase_YraL; 1. DR SUPFAM; SSF53790; SSF53790; 1. DR TIGRFAMs; TIGR00096; TIGR00096; 1. DR PROSITE; PS01296; RSMI; 1. PE 3: Inferred from homology; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01877}; KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|HAMAP- KW Rule:MF_01877}; Reference proteome {ECO:0000313|Proteomes:UP000580568}; KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP- KW Rule:MF_01877}; KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP- KW Rule:MF_01877}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP- KW Rule:MF_01877}. FT DOMAIN 3..202 FT /note="TP_methylase" FT /evidence="ECO:0000259|Pfam:PF00590" SQ SEQUENCE 279 AA; 31809 MW; C48D2A16DC3198D8 CRC64; MTKLYLVPTP IGNLKDITLR ALEVLKTVDV IAAEDTRQTL KLLNHYEIKK TLISYHKHNE YGKSEDIIGI INSGRSVAIV SDAGTPGISD PGEILVKRCI EENIQFEVLP GATATTTALV YSGFDTTKFM FRGFLPRENK DRIEVVDTLK DRSETIIFYE APHRLLSTLD FLKEAFGNRR IAICRELTKL HEEIVRVTIS EAISYFSNKQ PKGEFVLVLE GKSKEDIENE KKATWEDLSI EEHILRNINN GMEKKEAIKM VAKERKLPKS EVYKYSTNM //