ID A0A6P8KKL8_DROMA Unreviewed; 778 AA. AC A0A6P8KKL8; DT 02-DEC-2020, integrated into UniProtKB/TrEMBL. DT 02-DEC-2020, sequence version 1. DT 10-FEB-2021, entry version 2. DE SubName: Full=homeotic protein proboscipedia {ECO:0000313|RefSeq:XP_033163911.1}; GN Name=LOC117143349 {ECO:0000313|RefSeq:XP_033163911.1}; OS Drosophila mauritiana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7226 {ECO:0000313|Proteomes:UP000515162, ECO:0000313|RefSeq:XP_033163911.1}; RN [1] {ECO:0000313|RefSeq:XP_033163911.1} RP IDENTIFICATION. RC STRAIN=Mau12 {ECO:0000313|RefSeq:XP_033163911.1}; RC TISSUE=Whole Body {ECO:0000313|RefSeq:XP_033163911.1}; RG RefSeq; RL Submitted (OCT-2020) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, CC ECO:0000256|RuleBase:RU000682}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_033163911.1; XM_033308020.1. DR Proteomes; UP000515162; Genome assembly. DR CDD; cd00086; homeodomain; 1. DR InterPro; IPR009057; Homeobox-like_sf. DR InterPro; IPR001827; Homeobox_Antennapedia_CS. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR020479; Homeobox_metazoa. DR Pfam; PF00046; Homeodomain; 1. DR PRINTS; PR00024; HOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00032; ANTENNAPEDIA; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 4: Predicted; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}; KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. FT DOMAIN 193..253 FT /note="Homeobox" FT /evidence="ECO:0000259|PROSITE:PS50071" FT DNA_BIND 195..254 FT /note="Homeobox" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108" FT REGION 1..23 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 150..192 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 248..333 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 438..489 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 502..576 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 253..277 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 278..333 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 438..453 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 469..489 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 506..559 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 778 AA; 83171 MW; 2691D88CA105FB81 CRC64; MQEVCSSLDT TSMGTQIKSE SPLNPLQVQT GQTSMPVVGC GGAGVVGGVG VGVGQPGIGQ QGVPPVPAVL MVNKMTPNCD KRSADTAYWM TASEGGFINS QPSMAEFLNH LSPESPKIGT PVGSGAIGGV GVNVNVNVGV GVGYPVGVVP QTPDGMDSVP EYPWMKEKKT SRKSSNNNNQ GDNSITEFVP ENGLPRRLRT AYTNTQLLEL EKEFHFNKYL CRPRRIEIAA SLDLTERQVK VWFQNRRMKH KRQTLSKTDD EDNKDSLKGD DDQSDSNSNS KKSCQGCELP SDDIPDSTSN SRGHNNNTPS ATNNNPSAGS LTPNSSLETG ISSNLMGSTT VSASNVISAD SSVASSVSLD EDIEESSPIK VKKKDDGQVI KKEAVSTSSK ASPFGYENST PSLVSFRRDS DAAAVGNAPT SKAVGKKRFQ SAVNAIATPT PLSDSNSGNG NGNGGGGGPA GGYFPGYYPS PKQQQQLHPQ QQQLPQQQPQ DYYGKYDIEF AASPHHNPHN KQQTLHGEYL SPKPSAANFH QNSQQQQQND QFYYNYNDTN GTPYLNHQQQ HHHHAQHHQQ QQHHQNHVAD FEAPVNGPSN FNNGAYYDNM SFQQQAQAHQ HQAVVFQQQQ PHQPAAINHQ HMHHLGSGET YSALGLQMEN CEGYNNFGAA GTGGGYYEAG QQPPVPATHG HGHHPHHVQV PAQANAHIHA HHNSAAIPGG VGVGPPPTHI HGFAINGGPA GQGQAFGNNG STAAGTAAIS GLENSNSSDF NFLSNLANDF APEYYQLS //