ID A0A6P4JXR8_DROBP Unreviewed; 410 AA. AC A0A6P4JXR8; DT 02-DEC-2020, integrated into UniProtKB/TrEMBL. DT 02-DEC-2020, sequence version 1. DT 25-MAY-2022, entry version 6. DE SubName: Full=tumor susceptibility gene 101 protein {ECO:0000313|RefSeq:XP_017087656.1}; GN Name=LOC108119139 {ECO:0000313|RefSeq:XP_017087656.1}; OS Drosophila bipectinata (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=42026 {ECO:0000313|Proteomes:UP000515201, ECO:0000313|RefSeq:XP_017087656.1}; RN [1] {ECO:0000313|RefSeq:XP_017087656.1} RP IDENTIFICATION. RG RefSeq; RL Submitted (FEB-2021) to UniProtKB. CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV CC subfamily. {ECO:0000256|ARBA:ARBA00009594}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_017087656.1; XM_017232167.1. DR GeneID; 108119139; -. DR OMA; YMNFPQP; -. DR Proteomes; UP000515201; Unplaced. DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW. DR GO; GO:0006464; P:cellular protein modification process; IEA:InterPro. DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule. DR Gene3D; 3.10.110.10; -; 1. DR InterPro; IPR037202; ESCRT_assembly_dom. DR InterPro; IPR017916; SB_dom. DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD. DR InterPro; IPR008883; UEV_N. DR Pfam; PF05743; UEV; 1. DR Pfam; PF09454; Vps23_core; 1. DR SUPFAM; SSF140111; SSF140111; 1. DR SUPFAM; SSF54495; SSF54495; 1. DR PROSITE; PS51312; SB; 1. DR PROSITE; PS51322; UEV; 1. PE 3: Inferred from homology; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}; KW Endosome {ECO:0000256|ARBA:ARBA00022753}; KW Protein transport {ECO:0000256|ARBA:ARBA00022927, ECO:0000256|PROSITE- KW ProRule:PRU00644}; KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PROSITE- KW ProRule:PRU00644}. FT DOMAIN 3..146 FT /note="UEV" FT /evidence="ECO:0000259|PROSITE:PS51322" FT DOMAIN 344..410 FT /note="SB" FT /evidence="ECO:0000259|PROSITE:PS51312" FT REGION 222..241 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 262..289 FT /evidence="ECO:0000256|SAM:Coils" FT COILED 297..334 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 410 AA; 45096 MW; DA011A53A32BB5A0 CRC64; MPAVEEAQIT RYLSKYKYVG ATKKDVVDVV TTYRSLTYDL QRFVFNDGTA KDLFTLQGTI PVVYKNNTYH IPICIWLMDT HPQNAPMCFV KPTPTMQIKV SMYVDHNGKV YLPYLHDWQP HSSDLLSLIQ VMMVTFGDHP PVYSKPKEQI AAPYPNNSFM PQPGGAGPSS SYLPYPTAGG AGGGNFPPYP TGSNFGSPYP PAGGGPAGHG AGYPPYMNFP QPSGGYPPAG GYNPSSNASS TGTITEEHIK ASLISAVEDK LRRRLQEKVN QYQAEIETLN RTKSELVEGS AKIDSIISRL EREEVDLKKN IAVLKDKEEE LEKSLATLES AEAIDPDEAV TTTAPLYRQL LNAYADEAAT EDAIYYLGEG LRGGVIDLET FLKHVRTLSR KQFILRATMQ KCRQKAGLAG //