ID A0A6P4H739_DROTK Unreviewed; 492 AA. AC A0A6P4H739; DT 02-DEC-2020, integrated into UniProtKB/TrEMBL. DT 02-DEC-2020, sequence version 1. DT 25-MAY-2022, entry version 6. DE RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; GN Name=LOC108063759 {ECO:0000313|RefSeq:XP_017006448.1}; OS Drosophila takahashii (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=29030 {ECO:0000313|Proteomes:UP000515206, ECO:0000313|RefSeq:XP_017006448.1}; RN [1] {ECO:0000313|RefSeq:XP_017006448.1} RP IDENTIFICATION. RG RefSeq; RL Submitted (FEB-2021) to UniProtKB. CC -!- DOMAIN: A pair of annexin repeats may form one binding site for calcium CC and phospholipid. {ECO:0000256|RuleBase:RU003540}. CC -!- SIMILARITY: Belongs to the annexin family. CC {ECO:0000256|ARBA:ARBA00007831, ECO:0000256|RuleBase:RU003540}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_017006448.1; XM_017150959.1. DR GeneID; 108063759; -. DR Proteomes; UP000515206; Unplaced. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW. DR Gene3D; 1.10.220.10; -; 4. DR InterPro; IPR001464; Annexin. DR InterPro; IPR018502; Annexin_repeat. DR InterPro; IPR018252; Annexin_repeat_CS. DR InterPro; IPR037104; Annexin_sf. DR Pfam; PF00191; Annexin; 4. DR PRINTS; PR00196; ANNEXIN. DR SMART; SM00335; ANX; 4. DR SUPFAM; SSF47874; SSF47874; 1. DR PROSITE; PS00223; ANNEXIN_1; 2. DR PROSITE; PS51897; ANNEXIN_2; 4. PE 3: Inferred from homology; KW Annexin {ECO:0000256|ARBA:ARBA00023216, ECO:0000256|RuleBase:RU003540}; KW Calcium {ECO:0000256|RuleBase:RU003540}; KW Calcium/phospholipid-binding {ECO:0000256|RuleBase:RU003540}; KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU003540}. FT REGION 1..122 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 141..169 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 37..53 FT /note="Pro residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 54..68 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 69..100 FT /note="Pro residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 492 AA; 54470 MW; 94555F5DC6EEEF08 CRC64; MYPFGSGSGM PSYPPTSTNH HEPPRAPFGA GWVPPMQQNS PYPPQPHPPS QPSPQMHYHQ QQQYPGQQGA PAPYPPMSAP YPGAAAPSYP PYPSSNPYPG QFAPPLHQQH QQPPISNSPY PPDRGYTPAM TAGYDAGYGY GQGHGQGHGQ GHGHGQGYGN GQGQVHRSLP AHKEGTPTVV AAQGFDPVKD AHDLRKAMKG FGTDENALIN IICRRTNEQR QEIQRQYKTH FGKDLIEDIK SETSGNFEKL LVGLLRPIVD YYCAELNDAM AGLGTDEEVL IEILCTLSNM EIYTIKNQYL RLYGAHLESE LKSETSGNFK RLLTSLCTAA RDESGRVDPN AAKNDARELL KAGELRVGTD ESMFNMILCQ RNYQQLKMIF QEYEGMTGHS LEKAIKKEFS GDVMEGLIAI YRCVTNKAEY FASRLHKSMA GIGTNDTQLI RVIITRSEID MTDIKVAFER LYGKPLKSWI KGDTSGHYKH ALYALVGEQR SS //