ID A0A6P3TA66_SHEEP Unreviewed; 587 AA. AC A0A6P3TA66; B3F206; DT 02-DEC-2020, integrated into UniProtKB/TrEMBL. DT 02-DEC-2020, sequence version 1. DT 22-FEB-2023, entry version 11. DE SubName: Full=Cryptochrome 1 {ECO:0000313|EMBL:ABS44879.1}; OS Ovis aries (Sheep). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Caprinae; Ovis. OX NCBI_TaxID=9940 {ECO:0000313|EMBL:ABS44879.1}; RN [1] {ECO:0000313|EMBL:ABS44879.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=18953409; DOI=10.1371/journal.pone.0003530; RA Dardente H., Mendoza J., Fustin J.M., Challet E., Hazlerigg D.G.; RT "Implication of the F-Box Protein FBXL21 in circadian pacemaker function in RT mammals."; RL PLoS ONE 3:E3530-E3530(2008). RN [2] {ECO:0000313|EMBL:ABS44879.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=19341811; DOI=10.1016/j.cbpa.2009.03.016; RA Dardente H., Fustin J.M., Hazlerigg D.G.; RT "Transcriptional feedback loops in the ovine circadian clock."; RL Comp. Biochem. Physiol. 153:391-398(2009). CC -!- COFACTOR: CC Name=FAD; Xref=ChEBI:CHEBI:57692; CC Evidence={ECO:0000256|ARBA:ARBA00001974}; CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family. CC {ECO:0000256|ARBA:ARBA00005862}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF494243; ABS44879.1; -; mRNA. DR RefSeq; NP_001123207.1; NM_001129735.1. DR RefSeq; XP_012014825.1; XM_012159435.2. DR RefSeq; XP_012014834.1; XM_012159444.2. DR AlphaFoldDB; A0A6P3TA66; -. DR SMR; A0A6P3TA66; -. DR GeneID; 443263; -. DR KEGG; oas:443263; -. DR CTD; 1407; -. DR OrthoDB; 124765at2759; -. DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW. DR Gene3D; 1.25.40.80; -; 2. DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1. DR Gene3D; 3.40.50.620; HUPs; 1. DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf. DR InterPro; IPR036155; Crypto/Photolyase_N_sf. DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd. DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1. DR InterPro; IPR006050; DNA_photolyase_N. DR InterPro; IPR014729; Rossmann-like_a/b/a_fold. DR PANTHER; PTHR11455; CRYPTOCHROME; 1. DR PANTHER; PTHR11455:SF16; CRYPTOCHROME-1; 1. DR Pfam; PF00875; DNA_photolyase; 1. DR Pfam; PF03441; FAD_binding_7; 1. DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1. DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1. DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1. PE 2: Evidence at transcript level; KW Chromophore {ECO:0000256|ARBA:ARBA00022991}; KW FAD {ECO:0000256|ARBA:ARBA00022827}; KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}; KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543}; KW Receptor {ECO:0000256|ARBA:ARBA00022543}; KW Sensory transduction {ECO:0000256|ARBA:ARBA00022543}. SQ SEQUENCE 587 AA; 66454 MW; 4EEA4025338CE66D CRC64; MGVNAVHWFR KGLRLHDNPA LKECIQGADT IRCVYILDPW FAGSSNVGIN RWRFLLQCLE DLDANLRKLN SRLFVIRGQP ADVFPRLFKE WNITKLSIEY DSEPFGKERD AAIKKLATEA GVEVIIRISH TLYDLDKIIE LNGGQPPLTY KRFQTLISKM EPLEIPVETI TSEVMEKCTT PLSDDHDEKY GVPSLEELGF DTDGLPSAVW PGGETEALTR LERHLERKAW VANFERPRMN ANSLLASPTG LSPYLRFGCL SCRLFYFKLT DLYKKVKKNS SPPLSLYGQL LWREFFYTAA TNNPRFDKME GNPICVQIPW DKNPEALAKW AEGRTGFPWI DAIMTQLRQE GWIHHLARHA VACFLTRGDL WISWEEGMKV FEELLLDADW SINAGSWMWL SCSSFFQQFF HCYCPVGFGR RTDPNGDYIR RYLPVLRGFP AKYIYDPWNA PEGIQKVAKC LIGVNYPKPM VNHAEASRLN IERMKQIYQQ LSRYRGLGLL ASVPSNPNGN GGLMGYSPGE NIPGCSSSAS CTQGSGILHY AHGDSQQTHL LKQGRSSTAA GLGSGKRPSQ EEDTQSVGPK VQRQSTN //