ID   A0A6L5KTM8_ACIBA        Unreviewed;       432 AA.
AC   A0A6L5KTM8;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   13-SEP-2023, entry version 11.
DE   RecName: Full=C4-dicarboxylate transport protein {ECO:0000256|HAMAP-Rule:MF_01300};
GN   Name=dctA {ECO:0000256|HAMAP-Rule:MF_01300};
GN   ORFNames=F4T85_08470 {ECO:0000313|EMBL:MQZ68425.1}, F4U07_10505
GN   {ECO:0000313|EMBL:MQY85566.1};
OS   Acinetobacter baumannii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=470 {ECO:0000313|EMBL:MQZ68425.1, ECO:0000313|Proteomes:UP000420346};
RN   [1] {ECO:0000313|Proteomes:UP000354050, ECO:0000313|Proteomes:UP000420346}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMA26 {ECO:0000313|EMBL:MQZ68425.1,
RC   ECO:0000313|Proteomes:UP000420346}, and AMA5
RC   {ECO:0000313|EMBL:MQY85566.1, ECO:0000313|Proteomes:UP000354050};
RA   Maria R.S., Adams M.D.;
RT   "Distinct mechanisms of dissemination of NDM-1 metallo-beta-betalactamase
RT   in Acinetobacter species spp. in Argentina.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate across the membrane.
CC       {ECO:0000256|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01300};
CC       Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01300}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC       ECO:0000256|HAMAP-Rule:MF_01300}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MQZ68425.1}.
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DR   EMBL; VYSL01000012; MQY85566.1; -; Genomic_DNA.
DR   EMBL; VYTH01000009; MQZ68425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6L5KTM8; -.
DR   Proteomes; UP000354050; Unassembled WGS sequence.
DR   Proteomes; UP000420346; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR   PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01300};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01300};
KW   Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|HAMAP-Rule:MF_01300};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW   Rule:MF_01300};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW   Rule:MF_01300};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01300}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        59..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        89..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        162..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        199..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        231..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        319..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT   TRANSMEM        358..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   432 AA;  46247 MW;  E8039128CDCB66D7 CRC64;
     MDFNTLDQET VQKKQKFHQI LYVQVIFAII LGILIGHFYP ELGESLKPLG DAFIKIVKMI
     IAPVIFLTVV TGIASMTNMS RVGRVTGKAM LYFLTFSSLA LVVGMIVANI IQPGKGLNID
     PATLVNDKVN SYVEKAHATN ITDFFMNIIP QTLVSPLAGG EILQVLFVAV LFGISLAALG
     DRARPITDFL NNLTAPVFYL VGMLMKLAPI GAFGAMAFTI GAYGIESIGN LLLLIMTFYI
     TAVLFVLIIL GAVARYNGFS IIDLIRYIKD ELWLVLGTSS SEAALPSLMD KMQKAGCEKS
     VVGLVIPTGY SFNLDGTNIY MTMAALFIAQ ACNVDLSIGE QVALLLVAMV SSKGAAGVTG
     AGFITLAATL SVVPAVPVAG MALILGIDRF MSDCRALTNL IGNACATIVV ARWDKALDKD
     VLDKALRKSK TN
//