ID   A0A6J3IAF3_SAPAP        Unreviewed;       417 AA.
AC   A0A6J3IAF3;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   03-MAY-2023, entry version 10.
DE   SubName: Full=Cobalamin binding intrinsic factor {ECO:0000313|RefSeq:XP_032139210.1};
GN   Name=CBLIF {ECO:0000313|RefSeq:XP_032139210.1};
OS   Sapajus apella (Brown-capped capuchin) (Cebus apella).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Cebinae; Sapajus.
OX   NCBI_TaxID=9515 {ECO:0000313|Proteomes:UP000504640, ECO:0000313|RefSeq:XP_032139210.1};
RN   [1] {ECO:0000313|RefSeq:XP_032139210.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_032139210.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the eukaryotic cobalamin transport proteins
CC       family. {ECO:0000256|ARBA:ARBA00006449}.
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DR   RefSeq; XP_032139210.1; XM_032283319.1.
DR   AlphaFoldDB; A0A6J3IAF3; -.
DR   OrthoDB; 5361436at2759; -.
DR   Proteomes; UP000504640; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0015889; P:cobalamin transport; IEA:InterPro.
DR   GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.50.10.20; -; 1.
DR   Gene3D; 2.170.130.30; -; 1.
DR   InterPro; IPR002157; Cbl-bd_prot.
DR   InterPro; IPR027954; DUF4430.
DR   PANTHER; PTHR10559:SF15; COBALAMIN BINDING INTRINSIC FACTOR; 1.
DR   PANTHER; PTHR10559; TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR; 1.
DR   Pfam; PF01122; Cobalamin_bind; 1.
DR   Pfam; PF14478; DUF4430; 1.
DR   PROSITE; PS00468; COBALAMIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Cobalt transport {ECO:0000256|ARBA:ARBA00022426};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022426};
KW   Reference proteome {ECO:0000313|Proteomes:UP000504640};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transport {ECO:0000256|ARBA:ARBA00022426}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..417
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5027045077"
FT   DOMAIN          340..415
FT                   /note="DUF4430"
FT                   /evidence="ECO:0000259|Pfam:PF14478"
SQ   SEQUENCE   417 AA;  45465 MW;  B1B3C7E9F8D9583F CRC64;
     MAWFAVYLLS LLWAVAGTST QTRSSCYVPS AQEPLVNGIQ VLMESSVTSS AYPNPSILIA
     MNLVGAYSLE AQKLLTYQLM SSNADDLTIG QLGLTIMALT SSCRDPGNKV SILQRQMENW
     TPSSPNAEAS TFYGASLAIL ALCQKNSEAT LPIAVRFAKT LLANSSPFNV DTGAMATLAL
     TCMYNKIPVG SEEGYRALFG QVLKDIVENI SMRIKDNGII GGIYSTGLAM QALSVTPEPP
     TKEWNCKKTM DVILDEIKQG KFHNPMSIAQ ILPSLKGKTY LDVPQVTCSP DHEVQPTLPS
     PPGPVPTSTS NITVKYTINN QLRGVELLFN ETIDVSVKSG SVLLTVLEEA QRKNPMFKFE
     TTMTSWGLVV SSINNIAENV NHKTYWQFLS GVTPLDEGVA DYIPFNHEHI TANFTQY
//