ID A0A6J1N195_BICAN Unreviewed; 367 AA. AC A0A6J1N195; DT 07-OCT-2020, integrated into UniProtKB/TrEMBL. DT 07-OCT-2020, sequence version 1. DT 03-MAY-2023, entry version 11. DE SubName: Full=Protein decapentaplegic {ECO:0000313|RefSeq:XP_023936626.1}; GN Name=LOC112044871 {ECO:0000313|RefSeq:XP_023936626.1}; OS Bicyclus anynana (Squinting bush brown butterfly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea; OC Nymphalidae; Satyrinae; Satyrini; Mycalesina; Bicyclus. OX NCBI_TaxID=110368 {ECO:0000313|Proteomes:UP000504620, ECO:0000313|RefSeq:XP_023936626.1}; RN [1] {ECO:0000313|RefSeq:XP_023936626.1} RP IDENTIFICATION. RG RefSeq; RL Submitted (JAN-2023) to UniProtKB. CC -!- SIMILARITY: Belongs to the TGF-beta family. CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_023936626.1; XM_024080858.1. DR AlphaFoldDB; A0A6J1N195; -. DR KEGG; bany:112044871; -. DR OrthoDB; 2912454at2759; -. DR Proteomes; UP000504620; Unplaced. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW. DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW. DR CDD; cd13760; TGF_beta_BMP2_like; 1. DR Gene3D; 2.60.120.970; -; 1. DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1. DR InterPro; IPR029034; Cystine-knot_cytokine. DR InterPro; IPR001839; TGF-b_C. DR InterPro; IPR001111; TGF-b_propeptide. DR InterPro; IPR015615; TGF-beta-rel. DR InterPro; IPR017948; TGFb_CS. DR PANTHER; PTHR11848:SF263; PROTEIN DECAPENTAPLEGIC; 1. DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1. DR Pfam; PF00019; TGF_beta; 1. DR Pfam; PF00688; TGFb_propeptide; 1. DR SMART; SM00204; TGFB; 1. DR SUPFAM; SSF57501; Cystine-knot cytokines; 1. DR PROSITE; PS00250; TGF_BETA_1; 1. DR PROSITE; PS51362; TGF_BETA_2; 1. PE 3: Inferred from homology; KW Growth factor {ECO:0000256|ARBA:ARBA00023030, KW ECO:0000256|RuleBase:RU000354}; KW Reference proteome {ECO:0000313|Proteomes:UP000504620}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..19 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 20..367 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5026712032" FT DOMAIN 243..367 FT /note="TGF-beta family profile" FT /evidence="ECO:0000259|PROSITE:PS51362" FT REGION 233..260 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 246..260 FT /note="Basic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 367 AA; 41068 MW; 674A98AC21F6F543 CRC64; MRGACACAVV CALVALCAAR LDESARAAAE KQLLALLGLP RRPPPRARPP PVPRALRVLY DSRALPAAAA NTARSFHHTP TPLDERFPGD HRFRLFFNVS GVPADEVARG ADLSFQRAVG TTGRQRLLLY DVVRPGRRGH SEPILRLLDS VPLRPGEGIV NADALGAARR WLKEPKHNHG LLVRVLEEDA ASVSRDAKFP HVRVRRRVTD EEEEWRTAQP LLMLYTEDER ARASRETSER LTRSKRAAQR RGHRAHHRRK EAREICQRRP LFVDFADVGW SDWIVAPHGY DAYYCQGDCP FPLPDHLNGT NHAIVQTLVN SVNPATVPKA CCVPTQLSSI SMLYMDEVNN VVLKNYQDMM VVGCGCR //