ID A0A6J0J7L2_9PASS Unreviewed; 382 AA. AC A0A6J0J7L2; DT 07-OCT-2020, integrated into UniProtKB/TrEMBL. DT 07-OCT-2020, sequence version 1. DT 08-NOV-2023, entry version 12. DE SubName: Full=Neuroepithelial cell-transforming gene 1 protein-like {ECO:0000313|RefSeq:XP_017694937.1}; GN Name=LOC108509855 {ECO:0000313|RefSeq:XP_017694937.1}; OS Lepidothrix coronata (blue-crowned manakin). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Lepidothrix. OX NCBI_TaxID=321398 {ECO:0000313|Proteomes:UP000504624, ECO:0000313|RefSeq:XP_017694937.1}; RN [1] {ECO:0000313|RefSeq:XP_017694937.1} RP IDENTIFICATION. RG RefSeq; RL Submitted (JUL-2023) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_017694937.1; XM_017839448.1. DR AlphaFoldDB; A0A6J0J7L2; -. DR GeneID; 108509855; -. DR OrthoDB; 24012at2759; -. DR Proteomes; UP000504624; Unplaced. DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro. DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro. DR CDD; cd13224; PH_Net1; 1. DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1. DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1. DR InterPro; IPR035899; DBL_dom_sf. DR InterPro; IPR000219; DH-domain. DR InterPro; IPR001331; GDS_CDC24_CS. DR InterPro; IPR037853; Net1_PH. DR InterPro; IPR011993; PH-like_dom_sf. DR InterPro; IPR001849; PH_domain. DR PANTHER; PTHR46006:SF4; NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN; 1. DR PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1. DR Pfam; PF00169; PH; 1. DR Pfam; PF00621; RhoGEF; 1. DR SMART; SM00233; PH; 1. DR SMART; SM00325; RhoGEF; 1. DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1. DR SUPFAM; SSF50729; PH domain-like; 1. DR PROSITE; PS00741; DH_1; 1. DR PROSITE; PS50010; DH_2; 1. DR PROSITE; PS50003; PH_DOMAIN; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000504624}. FT DOMAIN 49..145 FT /note="DH" FT /evidence="ECO:0000259|PROSITE:PS50010" FT DOMAIN 175..290 FT /note="PH" FT /evidence="ECO:0000259|PROSITE:PS50003" FT REGION 296..382 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 327..341 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 363..382 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 382 AA; 43483 MW; A05D7C0B844498F5 CRC64; MVAHDELGGL LPIKRTIRVI DAQNQHFREQ EFPPGIDSWI SRSLQLPRLH AYKGYCSNQL AAKALLDQKK QDRRVQDFLQ RCLESPFSRK LDLWSFLDIP RSRLVKYPLL LKEILRHTPK DHPDIHILEE AISIIQGVLS DINLKKGESE CQYYIDKLEY LDEKQKDPRI ESSKALLCHG ELKNKNGHKL YVFLFQDILV LTRPVTRNER QAFQVYRQPI PVQELLLEDL QDGDVKMGGS FRGAFGNSDK AKNIFRVRFQ DSGPGHSHTL QANDVFHKQQ WVNCIRGAIA PFQSSAAPSE LQELPELREE SEENNPSVPN VPARRRRSGI SDVELDEGAA ERGSSVLDSG ESRGGGKAPR ASAGLRRSRE KQLSGKRKET LV //