ID A0A6H2GHU7_9ESCH Unreviewed; 389 AA. AC A0A6H2GHU7; DT 12-AUG-2020, integrated into UniProtKB/TrEMBL. DT 12-AUG-2020, sequence version 1. DT 07-OCT-2020, entry version 2. DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369}; GN Name=prpC {ECO:0000313|EMBL:QJC46982.1}; GN ORFNames=HGD79_10200 {ECO:0000313|EMBL:QJC46982.1}; OS Escherichia sp. SCLE84. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=2725997 {ECO:0000313|EMBL:QJC46982.1}; RN [1] {ECO:0000313|EMBL:QJC46982.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=SCLE84 {ECO:0000313|EMBL:QJC46982.1}; RA He J.; RT "Structural analysis of transposons."; RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+); CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287, CC ChEBI:CHEBI:57288; EC=2.3.3.16; CC Evidence={ECO:0000256|ARBA:ARBA00000308}; CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751}. CC -!- SIMILARITY: Belongs to the citrate synthase family. CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369, CC ECO:0000256|RuleBase:RU003406}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP051430; QJC46982.1; -; Genomic_DNA. DR RefSeq; WP_001285908.1; NZ_CP051430.1. DR UniPathway; UPA00223; UER00717. DR GO; GO:0050440; F:2-methylcitrate synthase activity; IEA:UniProtKB-EC. DR Gene3D; 1.10.230.10; -; 1. DR Gene3D; 1.10.580.10; -; 1. DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II. DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub. DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub. DR InterPro; IPR002020; Citrate_synthase. DR InterPro; IPR019810; Citrate_synthase_AS. DR InterPro; IPR024176; Citrate_synthase_bac-typ. DR InterPro; IPR036969; Citrate_synthase_sf. DR PANTHER; PTHR11739; PTHR11739; 1. DR Pfam; PF00285; Citrate_synt; 1. DR PIRSF; PIRSF001369; Citrate_synth; 1. DR PRINTS; PR00143; CITRTSNTHASE. DR SUPFAM; SSF48256; SSF48256; 1. DR TIGRFAMs; TIGR01800; cit_synth_II; 1. DR PROSITE; PS00480; CITRATE_SYNTHASE; 1. PE 3: Inferred from homology; KW Acyltransferase {ECO:0000313|EMBL:QJC46982.1}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369, KW ECO:0000256|RuleBase:RU003406, ECO:0000313|EMBL:QJC46982.1}. SQ SEQUENCE 389 AA; 43103 MW; 947B5163C1E1EB24 CRC64; MSDTTILQNS THVIKPKKSV ALSGVPAGNT ALCTVGKSGN DLHYRGYDIL DLAEHCEFEE VAHLLIHGKL PTRDELAAYK TKLKALRGLP ANVRTVLEAL PAASHPMDVM RTGVSALGCT LPEKEGHTVS GARDIADKLL ASLSSILLYW YHYSHNGERI QPETDDDSIG GHFLHLLHGE KPSQSWEKAM HISLVLYAEH EFNASTFTSR VIAGTGSDMY SAIIGAIGAL RGPKHGGANE VSLEIQQRYE TPDEAEADIR KRVENKEVVI GFGHPVYTIA DPRHQVIKRV AKQLSQEGGS LKMYNIADRL ETVMWESKKM FPNLDWFSAV SYNMMGVPTE MFTPLFVIAR VTGWAAHIIE QRQDNKIIRP SANYVGPEDR PFVALDKRQ //