ID A0A6H0CVG8_9ACTN Unreviewed; 970 AA. AC A0A6H0CVG8; DT 12-AUG-2020, integrated into UniProtKB/TrEMBL. DT 12-AUG-2020, sequence version 1. DT 03-MAY-2023, entry version 7. DE SubName: Full=Cellulose 1,4-beta-cellobiosidase {ECO:0000313|EMBL:QIS74117.1}; GN ORFNames=HB370_32435 {ECO:0000313|EMBL:QIS74117.1}; OS Streptomyces sp. DSM 40868. OC Bacteria; Actinomycetota; Streptomycetales; Streptomycetaceae; OC Streptomyces. OX NCBI_TaxID=2721173 {ECO:0000313|EMBL:QIS74117.1, ECO:0000313|Proteomes:UP000501663}; RN [1] {ECO:0000313|EMBL:QIS74117.1, ECO:0000313|Proteomes:UP000501663} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 40868 {ECO:0000313|EMBL:QIS74117.1, RC ECO:0000313|Proteomes:UP000501663}; RA David M., Lejeune C., Abreu S., Thibessard A., Leblond P., Chaminade P., RA Virolle M.-J.; RT "Is there a link between lipid content and antibiotic production in RT Streptomyces?"; RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP050504; QIS74117.1; -; Genomic_DNA. DR RefSeq; WP_030789136.1; NZ_CP050504.1. DR AlphaFoldDB; A0A6H0CVG8; -. DR Proteomes; UP000501663; Chromosome. DR GO; GO:0008810; F:cellulase activity; IEA:InterPro. DR GO; GO:0030247; F:polysaccharide binding; IEA:UniProtKB-UniRule. DR GO; GO:0030245; P:cellulose catabolic process; IEA:InterPro. DR Gene3D; 1.50.10.10; -; 1. DR Gene3D; 2.60.40.290; -; 1. DR Gene3D; 2.170.160.10; Endo-1,4-beta-glucanase f. Domain 2; 1. DR Gene3D; 4.10.870.10; Endo-1,4-beta-glucanase f. Domain 3; 1. DR Gene3D; 2.60.40.10; Immunoglobulins; 1. DR InterPro; IPR008928; 6-hairpin_glycosidase_sf. DR InterPro; IPR012341; 6hp_glycosidase-like_sf. DR InterPro; IPR001919; CBD2. DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf. DR InterPro; IPR012291; CBM2_carb-bd_dom_sf. DR InterPro; IPR023309; Endo-1-4-beta-glucanase_dom2. DR InterPro; IPR027390; Endoglucanase_F_dom3. DR InterPro; IPR000556; Glyco_hydro_48F. DR InterPro; IPR013783; Ig-like_fold. DR Pfam; PF17957; Big_7; 1. DR Pfam; PF00553; CBM_2; 1. DR Pfam; PF02011; Glyco_hydro_48; 1. DR PRINTS; PR00844; GLHYDRLASE48. DR SMART; SM00637; CBD_II; 1. DR SUPFAM; SSF49384; Carbohydrate-binding domain; 1. DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1. DR PROSITE; PS51173; CBM2; 1. PE 4: Predicted; KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277}; KW Glycosidase {ECO:0000256|ARBA:ARBA00023295}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Reference proteome {ECO:0000313|Proteomes:UP000501663}; KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}. FT SIGNAL 1..37 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 38..970 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5026080535" FT DOMAIN 35..144 FT /note="CBM2" FT /evidence="ECO:0000259|PROSITE:PS51173" SQ SEQUENCE 970 AA; 103043 MW; 59C62E5C4F2F44E6 CRC64; MDPGRRRTTA RRLWTAVAAA FALPLSMLAT GAETAHAAAV QCSVDYKTND WGSGFTADLT LTNRGTDAIN GWTLTYAYAG NQKLSGGWNG TWSQSGQSVT VKNASYNGTI AAGAAVSTGA QFTYSGANTA PTSFAVNGTT CAGAHQPPVT VLTSPSPGAV YSQGDAVPLA ATAAAADNAT ISKVEFYDDT ALLGTDTSAP YSLSASSLTV GSHSLVAKAY DSLGASATST PVGITVSSGP AVVASPSQLG VQQGKSGTFS VKLSTQPSAN VTVSTTRTDG NTGLSVTGGS SLTFTPSNWN TAQTVTITAD SSGTGSATFT ASATGHTKAT VTVTELPAAK AYDARFLDLY GKITDPANGY FSPEGIPYHS VETLIVEAPD HGHETTSEAY SYLLWLQAMY GKVTGDWSKF NGAWEIMEKY MIPTHADQPT NSFYNASKPA TYAPELDTPN EYPAKLDTSV SVGPDPIAGE LKSAYNSDDI YGMHWIQDVD NVYGYGNEPG KCEAGPTATG PSYINTFQRG VQESVWETVT QPTCDAFKYG GRNGYLDLFT GDSSYAKQWK FTNAPDADAR AVQAAYWADV WAKQQGKSGD VSATVAKAAK MGDYLRYAMY DKYFKKIGNC TSTSCPAGTG KDASHYLLSW YYAWGGATDT SAGWAWRIGS SHVHGGYQNP LAAYALSSFA DLKPKSATGA SDWGKSLQRQ LEFYQWLQSS EGGIAGGATN SWAGRYASPP AGTSTFYGMA YDPAPVYHDP PSNQWFGFQA WSMERVAEYY QQTGNAQAKA ILDKWVKWAL SKTTINPDGT YRIPSTLQWS GQPDTWNATS PGSNNGLHVT VADYTDDVGV AAAYAKTLTY YAAKSGDTAA KSTAKALLDG MWNNYQDSLG IAVPETRTDY SRFNEKVYVP SGWSGTMPNG DAINSSSTFS SIRSFYKSDP NWSKIEAYLK GGAAPVFTYH RFWAEADIAL AMGSYAELLE //