ID A0A674NVU9_TAKRU Unreviewed; 489 AA. AC A0A674NVU9; DT 17-JUN-2020, integrated into UniProtKB/TrEMBL. DT 17-JUN-2020, sequence version 1. DT 27-NOV-2024, entry version 19. DE SubName: Full=Immunoresponsive gene 1, like {ECO:0000313|Ensembl:ENSTRUP00000077609.1}; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu. OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000077609.1, ECO:0000313|Proteomes:UP000005226}; RN [1] {ECO:0000313|Ensembl:ENSTRUP00000077609.1, ECO:0000313|Proteomes:UP000005226} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21551351; RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S., RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.; RT "Integration of the genetic map and genome assembly of fugu facilitates RT insights into distinct features of genome evolution in teleosts and RT mammals."; RL Genome Biol. Evol. 3:424-442(2011). RN [2] {ECO:0000313|Ensembl:ENSTRUP00000077609.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (AUG-2024) to UniProtKB. CC -!- SIMILARITY: Belongs to the PrpD family. CC {ECO:0000256|ARBA:ARBA00006174}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A674NVU9; -. DR Ensembl; ENSTRUT00000080375.1; ENSTRUP00000077609.1; ENSTRUG00000031604.1. DR GeneTree; ENSGT00390000015700; -. DR Proteomes; UP000005226; Chromosome 14. DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter. DR GO; GO:0047613; F:aconitate decarboxylase activity; IEA:TreeGrafter. DR GO; GO:0006952; P:defense response; IEA:TreeGrafter. DR FunFam; 1.10.4100.10:FF:000002; Aconitate decarboxylase 1; 1. DR Gene3D; 1.10.4100.10; 2-methylcitrate dehydratase PrpD; 1. DR Gene3D; 3.30.1330.120; 2-methylcitrate dehydratase PrpD; 1. DR InterPro; IPR036148; MmgE/PrpD_sf. DR InterPro; IPR042183; MmgE/PrpD_sf_1. DR InterPro; IPR042188; MmgE/PrpD_sf_2. DR InterPro; IPR005656; MmgE_PrpD. DR InterPro; IPR045337; MmgE_PrpD_C. DR InterPro; IPR045336; MmgE_PrpD_N. DR PANTHER; PTHR16943; 2-METHYLCITRATE DEHYDRATASE-RELATED; 1. DR PANTHER; PTHR16943:SF14; ZGC:154020; 1. DR Pfam; PF19305; MmgE_PrpD_C; 1. DR Pfam; PF03972; MmgE_PrpD_N; 1. DR SUPFAM; SSF103378; 2-methylcitrate dehydratase PrpD; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000005226}. FT DOMAIN 38..274 FT /note="MmgE/PrpD N-terminal" FT /evidence="ECO:0000259|Pfam:PF03972" FT DOMAIN 306..476 FT /note="MmgE/PrpD C-terminal" FT /evidence="ECO:0000259|Pfam:PF19305" SQ SEQUENCE 489 AA; 53798 MW; 57620B17CED7020D CRC64; MRQKAFKPAW ASRRLHKSAV EVLQHPEPED TITSSYGKFI SNIKAEHLSP VVLQRSKRMV LDSIGVGLIG STTDVFALAL QHCQHMYAHD EISSVYGRRD TKLSPTLAAF VNGVATHSMD FDDTWHPATH PSGAVLPAVL AISDMMPANC KPSGLDLLLA FNVGIEIQGR LMRFSNEAHN IPKRFHPPSV VGTMGSAAAC ARLLSLDQSQ CSHALAIAAS LSGAPMANAA TQSKPLHIGN ASRLGLEAAL LASRGLEAST QILDAVDGVS GFSAFYEDYK PCMLESPNDY GHTFLLETQD MGFKRFPAHL GMHWVADAAT NIYKLLLEYG PGEVQIQDIL IRTPKSKYIN RPFPKSKHEA RHSFQFNTCS ALLDGEVTVQ SFTPTAMTRP DLLALLNLVR VEHPHDNPAN FNQMYGEVQV TLVGGNVLRG RCDTFYGHWR NPLTNESLRK KFRSNAGVVL PREKVEGLID VVEELEQLED CRVLLSQLQ //