ID A0A654EGZ2_ARATH Unreviewed; 200 AA. AC A0A654EGZ2; DT 22-APR-2020, integrated into UniProtKB/TrEMBL. DT 22-APR-2020, sequence version 1. DT 27-NOV-2024, entry version 17. DE RecName: Full=Cyclin-dependent kinase inhibitor {ECO:0000256|PIRNR:PIRNR017811}; GN ORFNames=AN1_LOCUS4080 {ECO:0000313|EMBL:VYS48599.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:VYS48599.1, ECO:0000313|Proteomes:UP000426265}; RN [1] {ECO:0000313|EMBL:VYS48599.1, ECO:0000313|Proteomes:UP000426265} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. An-1 {ECO:0000313|Proteomes:UP000426265}; RA Jiao W.-B., Schneeberger K.; RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm CC {ECO:0000256|ARBA:ARBA00004642}. CC -!- SIMILARITY: Belongs to the CDI family. ICK/KRP subfamily. CC {ECO:0000256|ARBA:ARBA00010274, ECO:0000256|PIRNR:PIRNR017811}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CACRSJ010000104; VYS48599.1; -; Genomic_DNA. DR AlphaFoldDB; A0A654EGZ2; -. DR Proteomes; UP000426265; Unassembled WGS sequence. DR ExpressionAtlas; A0A654EGZ2; baseline and differential. DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:UniProtKB-UniRule. DR GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro. DR FunFam; 4.10.365.10:FF:000005; Cyclin-dependent kinase inhibitor 7; 1. DR Gene3D; 4.10.365.10; p27; 1. DR InterPro; IPR003175; CDI_dom. DR InterPro; IPR044898; CDI_dom_sf. DR InterPro; IPR044275; KRP. DR PANTHER; PTHR46776; CYCLIN-DEPENDENT KINASE INHIBITOR 4-RELATED; 1. DR PANTHER; PTHR46776:SF9; CYCLIN-DEPENDENT KINASE INHIBITOR 7; 1. DR Pfam; PF02234; CDI; 1. DR PIRSF; PIRSF017811; CDK_inhib_pln; 1. PE 3: Inferred from homology; KW Cell cycle {ECO:0000256|ARBA:ARBA00023306}; KW Protein kinase inhibitor {ECO:0000256|ARBA:ARBA00023013, KW ECO:0000256|PIRNR:PIRNR017811}. FT DOMAIN 154..198 FT /note="Cyclin-dependent kinase inhibitor" FT /evidence="ECO:0000259|Pfam:PF02234" FT REGION 1..87 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 122..162 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..36 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 37..59 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 134..157 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 200 AA; 22688 MW; 468E812FBA868649 CRC64; MSLREMSETK PKRDYEYEGS DIKRMRLDDD DDVLRSPTRT LSSSSSSSLA YSVSDSGGFC SVALSEEEDD HRSSSVSSGC SSSETNEIAT RLPFSDLEAH EISETEISTL LTNNFRKQGI SSSENLGETA EMDSATTEMR DQRKTEKKKK MEKSPTQAEL DDFFSAAERY EQKRFTEKYN YDIVNDTPLE GRYQWVSLKP //