ID   A0A5S9F0S3_RHOMR        Unreviewed;      1348 AA.
AC   A0A5S9F0S3;
DT   22-APR-2020, integrated into UniProtKB/TrEMBL.
DT   22-APR-2020, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=RmaAA338_18730 {ECO:0000313|EMBL:BBM73008.1};
OS   Rhodothermus marinus (Rhodothermus obamensis).
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Rhodothermaceae;
OC   Rhodothermus.
OX   NCBI_TaxID=29549 {ECO:0000313|EMBL:BBM73008.1, ECO:0000313|Proteomes:UP000464918};
RN   [1] {ECO:0000313|Proteomes:UP000464918}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AA3-38 {ECO:0000313|Proteomes:UP000464918};
RA   Tomariguchi N., Miyazaki K.;
RT   "Complete Genome Sequences of Rhodothermus marinus Strains AA2-13 and AA3-
RT   38, Isolated from Arima Onsen Hot Spring in Japan.";
RL   Microbiol. Resour. Announc. 9:e01475-19(2020).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP019797; BBM73008.1; -; Genomic_DNA.
DR   Proteomes; UP000464918; Chromosome.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00890; Prefoldin; 1.
DR   CDD; cd00156; REC; 1.
DR   CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011110; Reg_prop.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR   PANTHER; PTHR45339:SF6; RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF07494; Reg_prop; 6.
DR   Pfam; PF00072; Response_reg; 2.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00448; REC; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 2.
DR   SUPFAM; SSF52172; CheY-like; 2.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW   ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1348
FT                   /note="histidine kinase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030137756"
FT   DOMAIN          822..1042
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   DOMAIN          1061..1183
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          1225..1343
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   REGION          1191..1228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          760..822
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1191..1223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1115
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT   MOD_RES         1274
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   1348 AA;  152557 MW;  0984231B1C14AF7F CRC64;
     MLRRPCFHWF YGLALLIALP ALAQQHYFHT YTSADGLSQL VVQALLQDRE GYVWIGTQAG
     LNRFDGFGFE TFSLRDGLVG DFIWALAEGP DGSLWIGTRN GLSRREPNGR FTSFSLAEGL
     PSPDVRALTV TADGTVWIGT PRGLAYLKDD RIERVETLGT QAIYDFLIDR KRQLYVATQN
     GLYRWAPPRW VPVAPFTEQP VYRLLEDLEG RLWVSTADAL VVLAGGRRVA RYTEKDGLKG
     LPARDLAVDS LGVVWVVTLE GLGRIDATGV RWLTEANGLP TSVLNALMVD REGMLWLGSL
     KGVSQFRGRA FTNYTVRDGL ADNLVRPIVR DRQGYLWVGT RRGLNRFDGR RWAVYTEKDG
     LPSEFVRSLF LDSRGRLWIG TLRGLALYEN GRFHRVPGFP HEASVMSIVE DHQGRIWLAA
     QNLGVFRQNG ARFIPVEVPG QVFTDARLLV DRRGHVWISG DMGLSRWDGR HWRTFTSKDG
     LAGNNPYFLA EDLQGRIWFG YHAALGITVY DPEQNRFRTY TTADGLHNDA VYSIGVDHQN
     NIWIGTSRGV DRFDGERFVN YSPLEGYASY ESNAGGFFAD VDGTLWFGTM DGLSHYNPRE
     DLWNDRPPRV RLTYLQLGDR PVNPDSLVQV SYKANTLTAR VALLSFFGAE QIQLRYRLRS
     MDTDWNLTFQ PLQRNRSWLR KPISSEEGWR PLESPTIFLT NLPAGFYVLE VQARKPTSDW
     SRPAAARFEI TPPFWQTAWF AALVVTLLGL LVGGIHRYRI YRIEQQKEQL EALVQERTAE
     LQAQKRQLKA TLEDLRQTKE ELERANEELV RASRLKSEFL ANMSHEIRTP MNGVLGMTEL
     LLEMDLTKEQ RECVEIIHRS GETLLTILND ILDFSKIEAG RLELENIDFN LQETIEDVIT
     LFAPRAAAKQ LELICFIEER ALEVQGDPHR LRQVLSNLIG NAIKFTERGE VVVEAELERL
     NERRAYWRIS VRDTGIGIPP DRLSHLFQPF TQLDGSTTRR YGGTGLGLAI SKQLVEMMGG
     TIGVESEVGK GSTFTVRIPF RLSSQRKLNG DERRALLKDV RVLIVDDNET NREILRRQTL
     GWGMVPTLAR SGAEALELMR AAARQGHPFE LAILDMMMPE MDGIMLAREI KQDPALAATP
     LILLSSYLFT REDHRAMDET LFAAVLSKPT RQSYLFNTLV RVLQEMRSVA AEKQQPQRTE
     SATVPDQSDS SDAPSTTPRS TSRGHLLLAE DNPVNQKVAL YHLERLGYTC DVVSDGKQAV
     EAALRGGYDA ILMDVHMPVM DGFEATALIR EHEANLGRHT PIIAMTANAL RGERERCLEA
     GMDDYIAKPF KKDELKTVLE RWIQKAEA
//