ID A0A5P2TZ84_KLULC Unreviewed; 172 AA. AC A0A5P2TZ84; DT 22-APR-2020, integrated into UniProtKB/TrEMBL. DT 22-APR-2020, sequence version 1. DT 19-JAN-2022, entry version 5. DE RecName: Full=Cytochrome b5 heme-binding domain-containing protein {ECO:0000259|PROSITE:PS50255}; GN ORFNames=KDRO_A00390 {ECO:0000313|EMBL:QEU58026.1}; OS Kluyveromyces lactis (Yeast) (Candida sphaerica). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces. OX NCBI_TaxID=28985 {ECO:0000313|EMBL:QEU58026.1, ECO:0000313|Proteomes:UP000323107}; RN [1] {ECO:0000313|Proteomes:UP000323107} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 2105 {ECO:0000313|Proteomes:UP000323107}; RA Ortiz-Merino R.A., Braun-Galleani S., Wolfe K.H., Morrissey J.P.; RT "Kluyveromyces lactis var. drosophilarum CBS 2105 Genome assembly."; RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the cytochrome b5 family. CC {ECO:0000256|RuleBase:RU362121}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|RuleBase:RU362121}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP042455; QEU58026.1; -; Genomic_DNA. DR VEuPathDB; FungiDB:KLLA0_F27577g; -. DR Proteomes; UP000323107; Chromosome 1. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR Gene3D; 3.10.120.10; -; 1. DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd. DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf. DR InterPro; IPR018506; Cyt_B5_heme-BS. DR Pfam; PF00173; Cyt-b5; 1. DR PRINTS; PR00363; CYTOCHROMEB5. DR SMART; SM01117; Cyt-b5; 1. DR SUPFAM; SSF55856; SSF55856; 1. DR PROSITE; PS00191; CYTOCHROME_B5_1; 1. DR PROSITE; PS50255; CYTOCHROME_B5_2; 1. PE 3: Inferred from homology; KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU362121}; KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU362121}; KW Membrane {ECO:0000256|RuleBase:RU362121}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|RuleBase:RU362121}; KW Transmembrane {ECO:0000256|RuleBase:RU362121}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362121}. FT TRANSMEM 101..122 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362121" FT TRANSMEM 134..153 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362121" FT DOMAIN 3..63 FT /note="Cytochrome b5 heme-binding" FT /evidence="ECO:0000259|PROSITE:PS50255" SQ SEQUENCE 172 AA; 19646 MW; 1E6E2131AA4A3CDA CRC64; MRDPLISMDE VARHSSRSDC WTVIHGKVYD ITSFLHKHPG GAQVLLKYAG KDSTLQFDDI GHSMESLAYD LDPGALKGTL YLPISKSTHN SDNEDDSSLP YFLSASFLPS SLLWITSIYQ AIRKFFLLER DTRIWLFSTI IFFCVLTLGF IHWSHDHNII DNNDYGVPAW MD //