ID A0A5N4ARM8_PHOPY Unreviewed; 347 AA. AC A0A5N4ARM8; DT 26-FEB-2020, integrated into UniProtKB/TrEMBL. DT 26-FEB-2020, sequence version 1. DT 12-AUG-2020, entry version 4. DE RecName: Full=Lipase domain-containing protein {ECO:0000259|Pfam:PF00151}; GN ORFNames=PPYR_07885 {ECO:0000313|EMBL:KAB0800005.1}; OS Photinus pyralis (Common eastern firefly) (Lampyris pyralis). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Holometabola; Coleoptera; Polyphaga; Elateriformia; Elateroidea; OC Lampyridae; Lampyrinae; Photinus. OX NCBI_TaxID=7054 {ECO:0000313|EMBL:KAB0800005.1, ECO:0000313|Proteomes:UP000327044}; RN [1] {ECO:0000313|EMBL:KAB0800005.1, ECO:0000313|Proteomes:UP000327044} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1611_PpyrPB1 {ECO:0000313|EMBL:KAB0800005.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:KAB0800005.1}; RX PubMed=30324905; RA Fallon T.R., Lower S.E., Chang C.H., Bessho-Uehara M., Martin G.J., RA Bewick A.J., Behringer M., Debat H.J., Wong I., Day J.C., Suvorov A., RA Silva C.J., Stanger-Hall K.F., Hall D.W., Schmitz R.J., Nelson D.R., RA Lewis S.M., Shigenobu S., Bybee S.M., Larracuente A.M., Oba Y., Weng J.K.; RT "Firefly genomes illuminate parallel origins of bioluminescence in RT beetles."; RL Elife 7:e36495-e36495(2018). CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family. CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAB0800005.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; VVIM01000005; KAB0800005.1; -; Genomic_DNA. DR Proteomes; UP000327044; Unassembled WGS sequence. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro. DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro. DR CDD; cd00707; Pancreat_lipase_like; 1. DR Gene3D; 3.40.50.1820; -; 1. DR InterPro; IPR029058; AB_hydrolase. DR InterPro; IPR013818; Lipase/vitellogenin. DR InterPro; IPR033906; Lipase_N. DR InterPro; IPR000734; TAG_lipase. DR PANTHER; PTHR11610; PTHR11610; 1. DR Pfam; PF00151; Lipase; 1. DR PRINTS; PR00821; TAGLIPASE. DR SUPFAM; SSF53474; SSF53474; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000327044}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..347 FT /note="Lipase domain-containing protein" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5024433105" FT DOMAIN 46..297 FT /note="Lipase" FT /evidence="ECO:0000259|Pfam:PF00151" SQ SEQUENCE 347 AA; 38399 MW; F14402DE6101383B CRC64; MKGAILLALA CLSVAAASQD RQMMLLDLPK DILGELMALL KGQKVVKSIQ CTDPKPNDIE LLLYTRHQKY DPVVLDVFAP SPIKSDKPVI FITHGWLQDI KDPQLQDLKN AYLERYDSDV VMVNWGKLAW DLYARTACKV PKIAQIIADY LCQVNYEKGM PLENVQLVGH SIGAHLVGFV GQFTQQMCNK RVGRITGLDP AGPLFNDAPT AERLDKSDAD FVDIIHTNSK TFGYSDPIGH ADFYASCGTF QSSCVIPDFK LDKLINMPMD AVFCSHRRSV DYMIESVLSS NFVATECKYC PIGCPPVIAL VTRPGKAILG QQCSPDTRGK YYVPTNLKSP YATGGRI //