ID A0A5N3VSZ3_MUNMU Unreviewed; 658 AA. AC A0A5N3VSZ3; DT 26-FEB-2020, integrated into UniProtKB/TrEMBL. DT 26-FEB-2020, sequence version 1. DT 27-NOV-2024, entry version 16. DE RecName: Full=SAM domain-containing protein {ECO:0000259|PROSITE:PS50105}; DE Flags: Fragment; GN ORFNames=FD754_017149 {ECO:0000313|EMBL:KAB0352292.1}; OS Muntiacus muntjak (Barking deer) (Indian muntjac). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae; OC Muntiacinae; Muntiacus. OX NCBI_TaxID=9888 {ECO:0000313|EMBL:KAB0352292.1, ECO:0000313|Proteomes:UP000326458}; RN [1] {ECO:0000313|EMBL:KAB0352292.1, ECO:0000313|Proteomes:UP000326458} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UTSW_UCB_Mm {ECO:0000313|EMBL:KAB0352292.1}; RC TISSUE=Fibroblast cell line {ECO:0000313|EMBL:KAB0352292.1}; RA Mudd A.B., Bredeson J.V., Baum R., Hockemeyer D., Rokhsar D.S.; RT "Discovery of a novel chromosome fission-fusion reversal in muntjac."; RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single- CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAB0352292.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; VCEA01000002; KAB0352292.1; -; Genomic_DNA. DR AlphaFoldDB; A0A5N3VSZ3; -. DR Proteomes; UP000326458; Unassembled WGS sequence. DR GO; GO:0005783; C:endoplasmic reticulum; IEA:TreeGrafter. DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter. DR GO; GO:0005246; F:calcium channel regulator activity; IEA:InterPro. DR GO; GO:0005509; F:calcium ion binding; IEA:TreeGrafter. DR GO; GO:0032237; P:activation of store-operated calcium channel activity; IEA:InterPro. DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:TreeGrafter. DR GO; GO:0002115; P:store-operated calcium entry; IEA:TreeGrafter. DR CDD; cd09573; SAM_STIM1; 1. DR CDD; cd11722; SOAR; 1. DR FunFam; 1.10.150.50:FF:000009; Stromal interaction molecule 1; 1. DR FunFam; 1.10.287.3550:FF:000001; Stromal interaction molecule 1; 1. DR FunFam; 1.20.5.340:FF:000011; Stromal interaction molecule 1; 1. DR Gene3D; 1.10.287.3550; -; 1. DR Gene3D; 1.20.5.340; -; 1. DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1. DR InterPro; IPR001660; SAM. DR InterPro; IPR013761; SAM/pointed_sf. DR InterPro; IPR032393; SOAR. DR InterPro; IPR037608; STIM. DR InterPro; IPR037609; STIM1_SAM. DR PANTHER; PTHR15136:SF9; STROMAL INTERACTION MOLECULE 1; 1. DR PANTHER; PTHR15136; STROMAL INTERACTION MOLECULE HOMOLOG; 1. DR Pfam; PF07647; SAM_2; 1. DR Pfam; PF16533; SOAR; 1. DR SMART; SM00454; SAM; 1. DR SUPFAM; SSF47769; SAM/Pointed domain; 1. DR PROSITE; PS50105; SAM_DOMAIN; 1. PE 4: Predicted; KW Calcium {ECO:0000256|ARBA:ARBA00022837}; KW Calcium transport {ECO:0000256|ARBA:ARBA00022568}; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}; KW Ion transport {ECO:0000256|ARBA:ARBA00023065}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Signal {ECO:0000256|ARBA:ARBA00022729}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 85..103 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 3..61 FT /note="SAM" FT /evidence="ECO:0000259|PROSITE:PS50105" FT REGION 360..387 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 410..441 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 485..509 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 572..658 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 122..212 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 360..379 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:KAB0352292.1" SQ SEQUENCE 658 AA; 73630 MW; 0E7921B5457EB21A CRC64; YNWTVDEVVQ WLITYVELPQ YEETFRKLQL SGHAMPRLAV TNTTMTGTVL KMTDRSHRQK LQLKALDTVL FGPPLLTRHN HLKDFMLVVS IVIGVGGCWF AYIQNRYSKE HMKKMMKDLE GLHRAEQSLH DLQERLHKAQ EEHRTVEVEK VHLEKKLRDE INLAKQEAQR LKELREGTEN ERSRQKYAEE ELEQVREALR KAEKELESHS SWYAPEALQK WLQLTHEVEV QYYNIKKQNA EKQLLVAKEG AEKIKKKRNT LFGTFHVAHS SSLDDVDHKI LTAKQALSEV TAALRERLHR WQQIEILCGF QIVNNPGIHS LVAALNIDPS WMGSTRPNPA HFIMTDDVDD MDEEIVSPLS MQSPSLQTSV RQRLTEPQHG LGSQRLVEGE AGHFLTSRVS LRRMRSLSSG QSFSSEGLGT SAPPASASSS CSSATTTTTT TTSITTVHVH PVYYHHSTSY FLQMEPYPDP PPSDSTAVMP WHSESLGDLT HSDSESSLHM SDRQRLAPKP PQMIRAADEA LSAMTSNGSH RLIEGAHPGS LVDKLPDSPA LAKKALLALN HGLDKAHSLM ELSSPALPGG SPHLDSSRSH SPSPPDPDTP SPAGDSRALQ ASRNTRIPHL AGKKAAAEED NGSIGEETDS SPGRKKFPLK IFKKPLKK //