ID A0A5J6K8Z7_PERTU Unreviewed; 264 AA. AC A0A5J6K8Z7; DT 11-DEC-2019, integrated into UniProtKB/TrEMBL. DT 11-DEC-2019, sequence version 1. DT 27-MAR-2024, entry version 12. DE RecName: Full=Cytochrome b {ECO:0000256|ARBA:ARBA00013531}; DE AltName: Full=Complex III subunit 3 {ECO:0000256|ARBA:ARBA00031681}; DE AltName: Full=Complex III subunit III {ECO:0000256|ARBA:ARBA00032600}; DE AltName: Full=Cytochrome b-c1 complex subunit 3 {ECO:0000256|ARBA:ARBA00029812}; DE AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit {ECO:0000256|ARBA:ARBA00032818}; DE Flags: Fragment; GN Name=cytb {ECO:0000313|EMBL:QEV82731.1}; OS Peromyscus truei (Pinyon mouse). OG Mitochondrion {ECO:0000313|EMBL:QEV82731.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; OC Cricetidae; Neotominae; Peromyscus. OX NCBI_TaxID=89101 {ECO:0000313|EMBL:QEV82731.1}; RN [1] {ECO:0000313|EMBL:QEV82731.1} RP NUCLEOTIDE SEQUENCE. RA Rogers D.S., Lewis-Rogers N., Lewis-Rogers S., Ticul Alvarez Castaneda S., RA Rickart E.A.; RT "Mitochondrial cytochrome-b variation within Peromyscus truei reveals two RT strongly divergent haplogroups."; RL Spec. Publ. Mus. Tex. Tech. Univ. 70:0-0(2019). CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase complex CC (complex III or cytochrome b-c1 complex) that is part of the CC mitochondrial respiratory chain. The b-c1 complex mediates electron CC transfer from ubiquinol to cytochrome c. Contributes to the generation CC of a proton gradient across the mitochondrial membrane that is then CC used for ATP synthesis. {ECO:0000256|ARBA:ARBA00002566}. CC -!- SUBUNIT: The cytochrome bc1 complex contains 11 subunits: 3 respiratory CC subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and CC UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, CC UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of CC UQCRFS1). This cytochrome bc1 complex then forms a dimer. CC {ECO:0000256|ARBA:ARBA00011088}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane CC protein {ECO:0000256|ARBA:ARBA00004448}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MK871913; QEV82705.1; -; Genomic_DNA. DR EMBL; MK871939; QEV82731.1; -; Genomic_DNA. DR EMBL; MK871940; QEV82732.1; -; Genomic_DNA. DR EMBL; MK872044; QEV82836.1; -; Genomic_DNA. DR EMBL; MK872134; QEV82926.1; -; Genomic_DNA. DR AlphaFoldDB; A0A5J6K8Z7; -. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW. DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro. DR CDD; cd00284; Cytochrome_b_N; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR048259; Cytochrome_b_N_euk/bac. DR InterPro; IPR016174; Di-haem_cyt_TM. DR PANTHER; PTHR19271; CYTOCHROME B; 1. DR PANTHER; PTHR19271:SF16; CYTOCHROME B; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR SUPFAM; SSF81342; Transmembrane di-heme cytochromes; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 4: Predicted; KW Electron transport {ECO:0000256|ARBA:ARBA00022982}; KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128, ECO:0000313|EMBL:QEV82731.1}; KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792}; KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}; KW Ubiquinone {ECO:0000256|ARBA:ARBA00023075}. FT TRANSMEM 30..56 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 77..98 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 113..133 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 145..166 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 178..200 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 229..246 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 1..209 FT /note="Cytochrome b/b6 N-terminal region profile" FT /evidence="ECO:0000259|PROSITE:PS51002" FT DOMAIN 210..264 FT /note="Cytochrome b/b6 C-terminal region profile" FT /evidence="ECO:0000259|PROSITE:PS51003" FT NON_TER 264 FT /evidence="ECO:0000313|EMBL:QEV82731.1" SQ SEQUENCE 264 AA; 29804 MW; F0104B68E8E22171 CRC64; MTNIRKKHPL FKIINDSFID LPTPSNISSW WNFGSLLGIC LVIQILTGLF LAMHYTSDTT TAFSSVTHIC RDVNYGWLIR YMHANGASMF FICLFLHVGR GMYYGSYTFT ETWNIGIVLL FAVMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGTTL VEWIWGGFSV DKATLTRFFA FHFILPFIIT ALVIVHLLFL HETGSNNPSG LNSDADKIPF HPYYTIKDIL GILLLLMVLM ILVLFFPDIL GDPDNYTPAN PLNT //