ID A0A5H7MQK7_SALET Unreviewed; 140 AA. AC A0A5H7MQK7; DT 11-DEC-2019, integrated into UniProtKB/TrEMBL. DT 11-DEC-2019, sequence version 1. DT 26-FEB-2020, entry version 2. DE RecName: Full=L-fucose mutarotase {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00342433}; DE EC=5.1.3.29 {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00342799}; DE AltName: Full=Fucose 1-epimerase {ECO:0000256|HAMAP-Rule:MF_01662}; DE AltName: Full=Type-2 mutarotase {ECO:0000256|HAMAP-Rule:MF_01662}; GN Name=fucU {ECO:0000256|HAMAP-Rule:MF_01662, GN ECO:0000313|EMBL:ECF3834285.1}; GN ORFNames=E0U64_15850 {ECO:0000313|EMBL:ECF0954072.1}, E1821_15960 GN {ECO:0000313|EMBL:ECG8286419.1}, E1B31_15750 GN {ECO:0000313|EMBL:ECD4764268.1}, E2G14_12005 GN {ECO:0000313|EMBL:ECF2939576.1}, E2H02_15685 GN {ECO:0000313|EMBL:ECD5902171.1}, E4A02_12260 GN {ECO:0000313|EMBL:ECF3834285.1}, EUX01_01415 GN {ECO:0000313|EMBL:ECG2121817.1}, EWC91_05760 GN {ECO:0000313|EMBL:ECG2741998.1}, EWG08_15155 GN {ECO:0000313|EMBL:ECE8817793.1}, EWZ30_00780 GN {ECO:0000313|EMBL:ECD2223580.1}, EZX42_16590 GN {ECO:0000313|EMBL:ECD3427178.1}; OS Salmonella enterica subsp. enterica serovar Reading. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=165302 {ECO:0000313|EMBL:ECD4764268.1}; RN [1] {ECO:0000313|EMBL:ECD4764268.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=143518 {ECO:0000313|EMBL:ECF2939576.1}, 153169 RC {ECO:0000313|EMBL:ECD5902171.1}, 186573 RC {ECO:0000313|EMBL:ECG8286419.1}, 261481 RC {ECO:0000313|EMBL:ECD4764268.1}, 302603 RC {ECO:0000313|EMBL:ECF0954072.1}, 413193 RC {ECO:0000313|EMBL:ECD2223580.1}, 442158 RC {ECO:0000313|EMBL:ECE8817793.1}, 458062 RC {ECO:0000313|EMBL:ECG2741998.1}, 669761 RC {ECO:0000313|EMBL:ECG2121817.1}, 690336 RC {ECO:0000313|EMBL:ECD3427178.1}, and 708215 RC {ECO:0000313|EMBL:ECF3834285.1}; RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.; RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the anomeric conversion of L-fucose. CC {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00342439}. CC -!- CATALYTIC ACTIVITY: CC Reaction=alpha-L-fucose = beta-L-fucose; Xref=Rhea:RHEA:25580, CC ChEBI:CHEBI:42548, ChEBI:CHEBI:42589; EC=5.1.3.29; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01662, CC ECO:0000256|SAAS:SAAS01117945}; CC -!- PATHWAY: Carbohydrate metabolism; L-fucose metabolism. CC {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00010493}. CC -!- SUBUNIT: Homodecamer. {ECO:0000256|HAMAP-Rule:MF_01662, CC ECO:0000256|SAAS:SAAS00011474}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01662, CC ECO:0000256|SAAS:SAAS00011501}. CC -!- SIMILARITY: Belongs to the RbsD / FucU family. FucU mutarotase CC subfamily. {ECO:0000256|HAMAP-Rule:MF_01662, CC ECO:0000256|SAAS:SAAS00538952}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:ECD4764268.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAIEAE010000001; ECD2223580.1; -; Genomic_DNA. DR EMBL; AAIEKD010000012; ECD3427178.1; -; Genomic_DNA. DR EMBL; AAIEVF010000013; ECD4764268.1; -; Genomic_DNA. DR EMBL; AAIFFZ010000011; ECD5902171.1; -; Genomic_DNA. DR EMBL; AAIJJT010000021; ECE8817793.1; -; Genomic_DNA. DR EMBL; AAIKBL010000011; ECF0954072.1; -; Genomic_DNA. DR EMBL; AAIKSC010000018; ECF2939576.1; -; Genomic_DNA. DR EMBL; AAIKZN010000008; ECF3834285.1; -; Genomic_DNA. DR EMBL; AAINQN010000001; ECG2121817.1; -; Genomic_DNA. DR EMBL; AAINVR010000004; ECG2741998.1; -; Genomic_DNA. DR EMBL; AAIOXY010000011; ECG8286419.1; -; Genomic_DNA. DR RefSeq; WP_000920848.1; NZ_MZFM01000013.1. DR UniPathway; UPA00956; -. DR GO; GO:0036373; F:L-fucose mutarotase activity; IEA:UniProtKB-EC. DR Gene3D; 3.40.1650.10; -; 1. DR HAMAP; MF_01662; L_fucose_rotase; 1. DR InterPro; IPR023751; L-fucose_mutarotase. DR InterPro; IPR023750; RbsD-like_sf. DR InterPro; IPR007721; RbsD_FucU. DR Pfam; PF05025; RbsD_FucU; 1. DR SUPFAM; SSF102546; SSF102546; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|HAMAP-Rule:MF_01662, KW ECO:0000256|SAAS:SAAS00011465}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00420969}; KW Fucose metabolism {ECO:0000256|HAMAP-Rule:MF_01662, KW ECO:0000256|SAAS:SAAS00420975}; KW Isomerase {ECO:0000256|HAMAP-Rule:MF_01662, ECO:0000256|SAAS:SAAS00421475, KW ECO:0000313|EMBL:ECD4764268.1}. FT REGION 129..131 FT /note="Substrate binding" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01662" FT ACT_SITE 22 FT /note="Proton donor" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01662" FT BINDING 30 FT /note="Substrate" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01662" FT BINDING 107 FT /note="Substrate" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01662" SQ SEQUENCE 140 AA; 15254 MW; F80F469B5DC2F30D CRC64; MLKTISPLIS PTLLKVLAEM GHGDEIIFSD AHFPAHSLGP QVIRADGLSV SDLLRAIIPL FELDSYAPPL VMMAAVEGDT LDPSVEARYR DALSLEAPCP DIVRIDRYAF YERAQKAFAI VITGECAKYG NILLKKGVTP //