ID A0A5H2WW55_MACHE Unreviewed; 333 AA. AC A0A5H2WW55; DT 11-DEC-2019, integrated into UniProtKB/TrEMBL. DT 11-DEC-2019, sequence version 1. DT 17-JUN-2020, entry version 4. DE RecName: Full=Taste receptor type 2 {ECO:0000256|RuleBase:RU004424}; GN Name=TAS2R38 {ECO:0000313|EMBL:BBJ32819.1}; OS Macaca hecki (Heck's macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=90382 {ECO:0000313|EMBL:BBJ32819.1}; RN [1] {ECO:0000313|EMBL:BBJ32819.1} RP NUCLEOTIDE SEQUENCE. RA Widayati K.A., Yan X., Suzuki-Hashido N., Itoigawa A., Purba L.H.P.S., RA Fahri F., Terai Y., Suryobroto B., Imai H.; RT "Functional divergence of the bitter receptor TAS2R38 in Sulawesi RT macaques."; RL Ecol. Evol. 0:0-0(2019). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU004424}; Multi- CC pass membrane protein {ECO:0000256|RuleBase:RU004424}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor T2R family. CC {ECO:0000256|RuleBase:RU004423, ECO:0000256|SAAS:SAAS01066324}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LC473456; BBJ32819.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0033038; F:bitter taste receptor activity; IEA:InterPro. DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW. DR InterPro; IPR007960; T2R. DR InterPro; IPR030050; TAS2R38. DR PANTHER; PTHR11394:SF52; PTHR11394:SF52; 1. DR Pfam; PF05296; TAS2R; 1. PE 3: Inferred from homology; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU004424, KW ECO:0000256|SAAS:SAAS01066318}; KW Membrane {ECO:0000256|RuleBase:RU004424, ECO:0000256|SAAS:SAAS01066320, KW ECO:0000256|SAM:Phobius}; KW Receptor {ECO:0000256|RuleBase:RU004424, ECO:0000256|SAAS:SAAS01066312, KW ECO:0000313|EMBL:BBJ32819.1}; KW Sensory transduction {ECO:0000256|RuleBase:RU004424, KW ECO:0000256|SAAS:SAAS01066314}; KW Taste {ECO:0000256|RuleBase:RU004424, ECO:0000256|SAAS:SAAS01066315}; KW Transducer {ECO:0000256|RuleBase:RU004424, ECO:0000256|SAAS:SAAS01066316}; KW Transmembrane {ECO:0000256|RuleBase:RU004424, KW ECO:0000256|SAAS:SAAS01066323, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS01066317, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 20..43 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 55..76 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 96..118 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 144..168 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 191..218 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 249..271 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 277..298 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 333 AA; 37648 MW; A6EE4C88AD67B628 CRC64; MLTLTHICTV SSEVRSTFLF ISVLEFAVGF LTNAFISLVN FWDVVKRQPL SNSDCVLLCL SISRLFLHGL LFLSAIQLTH FQKLSEPLNH SYQAILMLWM IANQANLWLA ACLSLLYCSK LIRFSHTFLI CLANWVSRKI SQMLLGIILC SCICTVLCVW CFFGRLHFTV TTVLFMNNNT RLNWQIKDLN LFYSFLFCYL WSVPPFLLFL VSSGMLTVSL GRHMRTMKVY TRDSRDPSLE AHIKALKSLI SFFCFFAISS CAAFISVPLL ILWHDKIGVM VCVGIMAACP SGHAAVLISG NAKLRRAVTT ILLWAQSSLK VRADHMADSR TPC //