ID A0A5F4C6K1_CANLF Unreviewed; 1210 AA. AC A0A5F4C6K1; DT 11-DEC-2019, integrated into UniProtKB/TrEMBL. DT 11-DEC-2019, sequence version 1. DT 17-JUN-2020, entry version 3. DE SubName: Full=Nuclear factor related to kappaB binding protein {ECO:0000313|Ensembl:ENSCAFP00000049124}; GN Name=NFRKB {ECO:0000313|Ensembl:ENSCAFP00000049124, GN ECO:0000313|VGNC:VGNC:43786}; OS Canis lupus familiaris (Dog) (Canis familiaris). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis. OX NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000049124, ECO:0000313|Proteomes:UP000002254}; RN [1] {ECO:0000313|Ensembl:ENSCAFP00000049124, ECO:0000313|Proteomes:UP000002254} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000049124, RC ECO:0000313|Proteomes:UP000002254}; RX PubMed=16341006; DOI=10.1038/nature04338; RG Broad Sequencing Platform; RA Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., RA Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E., RA Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., RA Smith D.R., deJong P.J., Kirkness E.F., Alvarez P., Biagi T., Brockman W., RA Butler J., Chin C.-W., Cook A., Cuff J., Daly M.J., DeCaprio D., Gnerre S., RA Grabherr M., Kellis M., Kleber M., Bardeleben C., Goodstadt L., Heger A., RA Hitte C., Kim L., Koepfli K.-P., Parker H.G., Pollinger J.P., RA Searle S.M.J., Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A., RA Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P., RA Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L., Bachantsang P., RA Barry A., Bayul T., Benamara M., Berlin A., Bessette D., Blitshteyn B., RA Bloom T., Blye J., Boguslavskiy L., Bonnet C., Boukhgalter B., Brown A., RA Cahill P., Calixte N., Camarata J., Cheshatsang Y., Chu J., Citroen M., RA Collymore A., Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., RA Dhargay N., Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., RA Duffey N., Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S., RA Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K., Foley C., RA Franke A., Friedrich D., Gage D., Garber M., Gearin G., Giannoukos G., RA Goode T., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N., RA Hagopian D., Hagos B., Hall J., Healy C., Hegarty R., Honan T., Horn A., RA Houde N., Hughes L., Hunnicutt L., Husby M., Jester B., Jones C., Kamat A., RA Kanga B., Kells C., Khazanovich D., Kieu A.C., Kisner P., Kumar M., RA Lance K., Landers T., Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., RA LeVine S., Liu J., Liu X., Lokyitsang Y., Lokyitsang T., Lui A., RA Macdonald J., Major J., Marabella R., Maru K., Matthews C., McDonough S., RA Mehta T., Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., RA Miller K., Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., RA Naylor J., Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N., RA Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K., Osman S., RA Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F., Priest M., RA Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C., Rege F., RA Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S., Sharpe T., RA Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J., Smith C., RA Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., RA Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S., Thoulutsang D., RA Thoulutsang Y., Topham K., Topping I., Tsamla T., Vassiliev H., RA Venkataraman V., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., RA Wilson A., Yadav S., Yang S., Yang X., Young G., Yu Q., Zainoun J., RA Zembek L., Zimmer A., Lander E.S.; RT "Genome sequence, comparative analysis and haplotype structure of the RT domestic dog."; RL Nature 438:803-819(2005). RN [2] {ECO:0000313|Ensembl:ENSCAFP00000049124} RP IDENTIFICATION. RC STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000049124}; RG Ensembl; RL Submitted (OCT-2019) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAEX03003349; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCAFT00000075805; ENSCAFP00000049124; ENSCAFG00000010199. DR VGNC; VGNC:43786; NFRKB. DR GeneTree; ENSGT00390000016213; -. DR Proteomes; UP000002254; Chromosome 5. DR GO; GO:0031011; C:Ino80 complex; IEA:InterPro. DR Gene3D; 1.10.10.2430; -; 1. DR InterPro; IPR024867; NFRKB. DR InterPro; IPR025220; NFRKB_winged_dom. DR InterPro; IPR038106; NFRKB_winged_sf. DR PANTHER; PTHR13052; PTHR13052; 1. DR Pfam; PF14465; NFRKB_winged; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Reference proteome {ECO:0000313|Proteomes:UP000002254}. FT DOMAIN 379..478 FT /note="NFRKB_winged" FT /evidence="ECO:0000259|Pfam:PF14465" FT REGION 163..187 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 203..232 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 669..797 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 865..903 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 305..333 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 683..717 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 718..738 FT /note="Pro-rich" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 739..794 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 873..903 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1210 AA; 130040 MW; C5351B5BFA331B6C CRC64; MDSLDHMLTD PLELGPCGDG HGTRIMEDCL LGGTRVSLPE DLLEDPEIFF DVVSLSTWQE VLSDSQREHL QQFLPHFPED SFEQQNQLIL ALFSGENFRF GNPLHIAQKL FRDGHFNPEV VKYRQLCFKS QYKRYLTSQQ QYFHRLLKQI LASRSDLLEM ARRSGPALPF RQKRPSPSRT PEEREWRTQQ RYLKVLREVK EECGDTDLSS DEEDLSSWLP SSPARSPSPA VPLRVVPTLS TTDMKTADKI ELGDSDLKIM LKKHHEKRKH QPDHPDLLTG DLTLNDIMTR VNAGRKGSLA ALYDLAVLKK KVKEKEEKKK KKIKLIKSEA EDLAEPLSSA DGIPPLSQAP SPLAIPAIKE EPLEDLKPCL GINEISSSFF SLLLEILLLE GQASLPMLEE RVLDWQSSPA SSLNSWFSAA PNWAELVLPA LQYLAGESRA VPSSFSPFVE FKEKTQQWKL LGQSQDNEKE LAALFQLWLE TKDQAFCKQE NEDSSDATTP VPRVRTDYVV RPSTGEEKRV FQEQERYRYS QPHKAFTFRM HGFESVVGPV KGVFDKETSL NKAREHSLLR SDRPAYVTIL SLVRDAAARL PNGEGTRAEI CELLKDSQFL APDVTSTQVN TVVSGALDRL HYEKDPCVKY DIGRKLWIYL HRDRSEEEFE RIHQAQAAAA KARKALQQKP KPPSKVKSGS KESSLKVLGS GPSEQSQMSL SDSSMPPTPV TPVTPTTPAL PATPISPPPV SSVNKSGPTT VSEPAKSSSG VLLVSSPTMP QLGTMLSPAS SQTPPNSQAA ARVVSHSGSA GLPQVRVVAQ PGLPTVTQQS AGPAQTLPQM PAGPQIRVPA TATQTKVVPQ TVMATVPVKA QTAAATVQRP GPGQAGLTMT SLPATASPAS KPATSSPGSS APSASTAAVI QNVTGQNIIK QVAITGQLGV KPQAGNSIPL TATNFRIQGT TVVKVTPDLK PTEASSSAFR LMPALGVSVA DQKGKNTVAS SEAKPAATIR IVQGLGVMPP KAGQTITVAT HAKQGSSVAS GSGTVHTSAV SLPSMNAAVS KTVAVASGAA STPISIGTGA SAVRQVPVST TVVSTSQAGK LPTRITVPLS VISQPMKGKS VVTAPIIKGS LGANLSGLGR NIILTTMPAG TKLIAGNKPV SFLTAQQLQQ LQQQGQATQV RIQTVPASHL QQGTASGSSK AVSTVVVTTA PSPKQAPEQQ //