ID A0A5B9H8P4_9HIV1 Unreviewed; 288 AA. AC A0A5B9H8P4; DT 13-NOV-2019, integrated into UniProtKB/TrEMBL. DT 13-NOV-2019, sequence version 1. DT 03-AUG-2022, entry version 12. DE SubName: Full=Integrase {ECO:0000313|EMBL:QEE94042.1}; DE Flags: Fragment; GN Name=pol {ECO:0000313|EMBL:QEE94042.1}; OS Human immunodeficiency virus 1. OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:QEE94042.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:QEE94042.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=NACMR100 {ECO:0000313|EMBL:QEE94042.1}; RA Acharya A., Kanmogne G.D.; RT "Analyses of HIV-1 integrase sequences obtained from infected patients in RT Cameroon."; RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MK327868; QEE94042.1; -; Genomic_RNA. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro. DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW. DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR Gene3D; 1.10.10.200; -; 1. DR Gene3D; 2.30.30.10; -; 1. DR Gene3D; 3.30.420.10; -; 1. DR InterPro; IPR017856; Integrase-like_N. DR InterPro; IPR036862; Integrase_C_dom_sf_retrovir. DR InterPro; IPR001037; Integrase_C_retrovir. DR InterPro; IPR001584; Integrase_cat-core. DR InterPro; IPR003308; Integrase_Zn-bd_dom_N. DR InterPro; IPR012337; RNaseH-like_sf. DR InterPro; IPR036397; RNaseH_sf. DR Pfam; PF00552; IN_DBD_C; 1. DR Pfam; PF02022; Integrase_Zn; 1. DR Pfam; PF00665; rve; 1. DR SUPFAM; SSF46919; SSF46919; 1. DR SUPFAM; SSF50122; SSF50122; 1. DR SUPFAM; SSF53098; SSF53098; 1. DR PROSITE; PS50994; INTEGRASE; 1. DR PROSITE; PS51027; INTEGRASE_DBD; 1. DR PROSITE; PS50876; ZF_INTEGRASE; 1. PE 4: Predicted; KW DNA integration {ECO:0000256|ARBA:ARBA00022908}; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Endonuclease {ECO:0000256|ARBA:ARBA00022759}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Nuclease {ECO:0000256|ARBA:ARBA00022722}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00450}. FT DOMAIN 3..44 FT /note="Integrase-type" FT /evidence="ECO:0000259|PROSITE:PS50876" FT DOMAIN 54..204 FT /note="Integrase catalytic" FT /evidence="ECO:0000259|PROSITE:PS50994" FT DOMAIN 223..270 FT /note="Integrase-type" FT /evidence="ECO:0000259|PROSITE:PS51027" FT DNA_BIND 223..270 FT /note="Integrase-type" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00506" FT UNSURE 208 FT /note="I or L" FT /evidence="ECO:0000313|EMBL:QEE94042.1" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:QEE94042.1" SQ SEQUENCE 288 AA; 32100 MW; 3C6EB3DA7A448941 CRC64; FLNGIDKAQE DHEKYHSNWG AMANDFNLPP IVAKEIVASC NKCQLKGEAM HGQVDCSPGI WQLDCTHLEG KVILVAVHVA SGYIEAEVIP AETGQETAYF LLKLAARWPV KVIHTDNGSN FTSAAVKAAC WWADVKQEFG IPYNPQSQGV VESMNKELKK IIGQXRDQAE HLKTAVQMAV FIHNFKRKGG IGGYSAGERI IDIIASDLQT XELQKQITKI QNFRVYYRDS RDPIWKGPAK LLWKGEGAVV IQDNSDIKVV PRRKAKIIRD YGKQMAGDDC VAGRQDED //