ID A0A5B6V6K4_9ROSI Unreviewed; 559 AA. AC A0A5B6V6K4; DT 13-NOV-2019, integrated into UniProtKB/TrEMBL. DT 13-NOV-2019, sequence version 1. DT 22-FEB-2023, entry version 11. DE RecName: Full=poly(ADP-ribose) glycohydrolase {ECO:0000256|ARBA:ARBA00012255}; DE EC=3.2.1.143 {ECO:0000256|ARBA:ARBA00012255}; GN ORFNames=EPI10_000015 {ECO:0000313|EMBL:KAA3464788.1}; OS Gossypium australe. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium. OX NCBI_TaxID=47621 {ECO:0000313|EMBL:KAA3464788.1, ECO:0000313|Proteomes:UP000325315}; RN [1] {ECO:0000313|Proteomes:UP000325315} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. PA1801 {ECO:0000313|Proteomes:UP000325315}; RX PubMed=31479566; DOI=10.1111/pbi.13249; RA Cai Y., Cai X., Wang Q., Wang P., Zhang Y., Cai C., Xu Y., Wang K., RA Zhou Z., Wang C., Geng S., Li B., Dong Q., Hou Y., Wang H., Ai P., Liu Z., RA Yi F., Sun M., An G., Cheng J., Zhang Y., Shi Q., Xie Y., Shi X., Chang Y., RA Huang F., Chen Y., Hong S., Mi L., Sun Q., Zhang L., Zhou B., Peng R., RA Zhang X., Liu F.; RT "Genome sequencing of the Australian wild diploid species Gossypium RT australe highlights disease resistance and delayed gland morphogenesis."; RL Plant Biotechnol. J. 0:0-0(2019). CC -!- SIMILARITY: Belongs to the poly(ADP-ribose) glycohydrolase family. CC {ECO:0000256|ARBA:ARBA00009545}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAA3464788.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; SMMG02000007; KAA3464788.1; -; Genomic_DNA. DR AlphaFoldDB; A0A5B6V6K4; -. DR Proteomes; UP000325315; Chromosome 1. DR GO; GO:0004649; F:poly(ADP-ribose) glycohydrolase activity; IEA:UniProtKB-EC. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR GO; GO:0006282; P:regulation of DNA repair; IEA:InterPro. DR InterPro; IPR046372; PARG_cat. DR InterPro; IPR007724; Poly_GlycHdrlase. DR PANTHER; PTHR12837; POLY ADP-RIBOSE GLYCOHYDROLASE; 1. DR PANTHER; PTHR12837:SF0; POLY(ADP-RIBOSE) GLYCOHYDROLASE; 1. DR Pfam; PF05028; PARG_cat; 2. PE 3: Inferred from homology; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KAA3464788.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000325315}. FT DOMAIN 50..333 FT /note="Poly (ADP-ribose) glycohydrolase (PARG) catalytic" FT /evidence="ECO:0000259|Pfam:PF05028" FT DOMAIN 377..510 FT /note="Poly (ADP-ribose) glycohydrolase (PARG) catalytic" FT /evidence="ECO:0000259|Pfam:PF05028" FT ACT_SITE 228 FT /evidence="ECO:0000256|PIRSR:PIRSR607724-1" FT ACT_SITE 246 FT /evidence="ECO:0000256|PIRSR:PIRSR607724-1" FT ACT_SITE 247 FT /evidence="ECO:0000256|PIRSR:PIRSR607724-1" FT BINDING 231 FT /ligand="substrate" FT /evidence="ECO:0000256|PIRSR:PIRSR607724-2" FT BINDING 245 FT /ligand="substrate" FT /evidence="ECO:0000256|PIRSR:PIRSR607724-2" FT BINDING 286 FT /ligand="substrate" FT /evidence="ECO:0000256|PIRSR:PIRSR607724-2" SQ SEQUENCE 559 AA; 63503 MW; 1FD661EAE5588F67 CRC64; MSRGPDHSRV NCGEVLSIAI SDMRASLSLA DPLALSAPLG YALFFDELMS GADSRKWFAE DIPKLANLLL RLPSLLEVHY QNSRAYGYGL RILGPQQPGM VLLSQELIGA LLACSLFCLF PISNRGLKHL PTINFDQLFA SLYDSYSESQ ENQVRCIICY FQRICLQMPT GSVSFERKLL SLEHHPWQSF LSYPYADFWT KSTIPLCPFQ VHSSGLIEDH ATEALEVDFA NKYLGGGALH RGCVQEEIRF MINPELIAGM LFLPSMADNE AIEIVGAERF SDYKGYASSF RFSGDYVDKR SVDFLGRRKT RIVAIDALCS PRMKQYKLKY LLRIVAIDAL CSPRMKQYKL KYLLRIVAID ALCSPRMKQY KLKYLLRIVA IDALCSPRMK QYKLKYLLRE TNKAFCGFLD QSKYSQYKRL FKMNSVQLNE GSSLPIKAKG ESLTEEVRKS DEKSWHLEDC ENYIGIATGN WGCGAFGGDP EVKTIIQWLA ASQALRPFIS YYTFGLEALQ SLAQVTQWII LQKWNVGDLW NILIEYSSQK LRGEADVGFF AWLLPSLPK //