ID   A0A5B6UQD5_9ROSI        Unreviewed;       436 AA.
AC   A0A5B6UQD5;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   10-FEB-2021, entry version 9.
DE   RecName: Full=Glutamate dehydrogenase {ECO:0000256|PIRNR:PIRNR000185};
GN   ORFNames=EPI10_026981 {ECO:0000313|EMBL:KAA3460300.1};
OS   Gossypium australe.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=47621 {ECO:0000313|EMBL:KAA3460300.1, ECO:0000313|Proteomes:UP000325315};
RN   [1] {ECO:0000313|Proteomes:UP000325315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. PA1801 {ECO:0000313|Proteomes:UP000325315};
RX   PubMed=31479566; DOI=10.1111/pbi.13249;
RA   Cai Y., Cai X., Wang Q., Wang P., Zhang Y., Cai C., Xu Y., Wang K.,
RA   Zhou Z., Wang C., Geng S., Li B., Dong Q., Hou Y., Wang H., Ai P., Liu Z.,
RA   Yi F., Sun M., An G., Cheng J., Zhang Y., Shi Q., Xie Y., Shi X., Chang Y.,
RA   Huang F., Chen Y., Hong S., Mi L., Sun Q., Zhang L., Zhou B., Peng R.,
RA   Zhang X., Liu F.;
RT   "Genome sequencing of the Australian wild diploid species Gossypium
RT   australe highlights disease resistance and delayed gland morphogenesis.";
RL   Plant Biotechnol. J. 0:0-0(2019).
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
CC       {ECO:0000256|ARBA:ARBA00006382, ECO:0000256|PIRNR:PIRNR000185,
CC       ECO:0000256|RuleBase:RU004417}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAA3460300.1}.
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DR   EMBL; SMMG02000009; KAA3460300.1; -; Genomic_DNA.
DR   Proteomes; UP000325315; Chromosome 12.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   CDD; cd01076; NAD_bind_1_Glu_DH; 1.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DH.
DR   InterPro; IPR033524; Glu/Leu/Phe/Val_DH_AS.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DH_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DH_dimer_dom.
DR   InterPro; IPR014362; Glu_DH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR033922; NAD_bind_Glu_DH.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 2.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   SMART; SM00839; ELFV_dehydrog; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   3: Inferred from homology;
KW   NAD {ECO:0000256|PIRSR:PIRSR000185-2};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000185-2};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR000185, ECO:0000256|RuleBase:RU004417};
KW   Reference proteome {ECO:0000313|Proteomes:UP000325315}.
FT   DOMAIN          178..433
FT                   /note="ELFV_dehydrog"
FT                   /evidence="ECO:0000259|SMART:SM00839"
FT   ACT_SITE        102
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-1"
FT   BINDING         66
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-2"
FT   BINDING         90
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-2"
FT   BINDING         185
FT                   /note="NAD"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-2"
FT   BINDING         216
FT                   /note="NAD"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-2"
FT   BINDING         369
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-2"
FT   SITE            142
FT                   /note="Important for catalysis"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000185-3"
SQ   SEQUENCE   436 AA;  48028 MW;  F445F69291765F4E CRC64;
     MNALAATNRN FQLAARILGL DSKLHKSLLI PFREIKVECT VPRDDGSFVS YIGFRIQHDN
     ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVANLPYGG AKGGIGCNPR ELTVSELERV
     TRVFTQKIHD LIGIHRDVPA PDMGTNSQTM AWILDEYSKF HGYSPAVVTG KPIELGGSLG
     REAATGLGVV FATEFLLDEY GMSIANMKFA IQGFGNVGSW AASFIHQKGG KVVAVSDITG
     AVKNPNGIDI PALLKHKEKA YSLKDFEGGD AMDLNDVLVH ECDVLIPCAL GGVLNKYILC
     TSYKQSLPFI NSFLFPFKNQ KENAADVKAK FIIEAANHPT DPEADEILSR KGVIILPDIY
     ANSGGVTVSY FEWVQNIQGF MWEEEKVNYE LKRYMKRAFN DIKAMCHTHN CNLRMGAFAL
     GVNKVARATV LRGWEA
//