ID A0A5A7QAI9_STRAF Unreviewed; 571 AA. AC A0A5A7QAI9; DT 13-NOV-2019, integrated into UniProtKB/TrEMBL. DT 13-NOV-2019, sequence version 1. DT 29-MAY-2024, entry version 9. DE SubName: Full=Importin {ECO:0000313|EMBL:GER42269.1}; GN ORFNames=STAS_19045 {ECO:0000313|EMBL:GER42269.1}; OS Striga asiatica (Asiatic witchweed) (Buchnera asiatica). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; lamiids; Lamiales; Orobanchaceae; Buchnereae; Striga. OX NCBI_TaxID=4170 {ECO:0000313|EMBL:GER42269.1, ECO:0000313|Proteomes:UP000325081}; RN [1] {ECO:0000313|Proteomes:UP000325081} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. UVA1 {ECO:0000313|Proteomes:UP000325081}; RX PubMed=31522940; DOI=10.1016/j.cub.2019.07.086; RA Yoshida S., Kim S., Wafula E.K., Tanskanen J., Kim Y.M., Honaas L., RA Yang Z., Spallek T., Conn C.E., Ichihashi Y., Cheong K., Cui S., Der J.P., RA Gundlach H., Jiao Y., Hori C., Ishida J.K., Kasahara H., Kiba T., Kim M.S., RA Koo N., Laohavisit A., Lee Y.H., Lumba S., McCourt P., Mortimer J.C., RA Mutuku J.M., Nomura T., Sasaki-Sekimoto Y., Seto Y., Wang Y., Wakatake T., RA Sakakibara H., Demura T., Yamaguchi S., Yoneyama K., Manabe R.I., RA Nelson D.C., Schulman A.H., Timko M.P., dePamphilis C.W., Choi D., RA Shirasu K.; RT "Genome Sequence of Striga asiatica Provides Insight into the Evolution of RT Plant Parasitism."; RL Curr. Biol. 29:3041-3052.e4(2019). CC -!- CATALYTIC ACTIVITY: CC Reaction=Endohydrolysis of the N-glycosidic bond at one specific CC adenosine on the 28S rRNA.; EC=3.2.2.22; CC Evidence={ECO:0000256|RuleBase:RU004915}; CC -!- SIMILARITY: Belongs to the ribosome-inactivating protein family. CC {ECO:0000256|RuleBase:RU004915}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:GER42269.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BKCP01006294; GER42269.1; -; Genomic_DNA. DR AlphaFoldDB; A0A5A7QAI9; -. DR Proteomes; UP000325081; Unassembled WGS sequence. DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter. DR GO; GO:0005635; C:nuclear envelope; IEA:TreeGrafter. DR GO; GO:0030598; F:rRNA N-glycosylase activity; IEA:InterPro. DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW. DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW. DR GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW. DR GO; GO:0006606; P:protein import into nucleus; IEA:TreeGrafter. DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1. DR Gene3D; 3.40.420.10; Ricin (A subunit), domain 1; 1. DR InterPro; IPR011989; ARM-like. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR036041; Ribosome-inact_prot_sf. DR InterPro; IPR001574; Ribosome_inactivat_prot. DR InterPro; IPR016138; Ribosome_inactivat_prot_sub1. DR PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1. DR PANTHER; PTHR10997:SF9; IMPORTIN-9; 1. DR Pfam; PF00161; RIP; 1. DR SUPFAM; SSF48371; ARM repeat; 1. DR SUPFAM; SSF56371; Ribosome inactivating proteins (RIP); 1. PE 3: Inferred from homology; KW Hydrolase {ECO:0000256|RuleBase:RU004915}; KW Plant defense {ECO:0000256|RuleBase:RU004915}; KW Protein synthesis inhibitor {ECO:0000256|RuleBase:RU004915}; KW Reference proteome {ECO:0000313|Proteomes:UP000325081}; KW Toxin {ECO:0000256|RuleBase:RU004915}. SQ SEQUENCE 571 AA; 64786 MW; 0077F2AD4CA52848 CRC64; MNVDVFNTAS SYLKFLHQIR KSVTKPYHLM PDLHNAVLAE LPSKQTLAFK LNLVSAAYGQ INLAIKLTDL YMIGFNWICK EKMENKERWR RKRKKGGEIP HSGIRGGGSL DTRLELEKNI LRSPSIHHAV LKLKAPEWIY LLVINWAKLL RYHLKNYDHL TMVFCSLSVT TENEKETEDL LGLGTDFPLA LKSIRSVVLQ SSFQAIELMF VDALIKANDA LQIVAYIEYQ FYDTILKAIE TSSGQDFKDF MGIIGLCTRN ETGPMTRVSQ EFGDEVQAVR EAALYTVAAL ASVAEQLFLD EVEVGLFQAI IKAAGCIHPL VSIVFPYIEP ILSSNAPVDV IKEFFQVSFD LFVRIVLHHS KMKNATQCLA ALVSVWKQDM LSWSGVPAFT MRSLLDVAWK LLDPELETSR SLFVGSYILQ LILHLHSQMA QHIRDLVTAL MRRMQCSQIA GLKCSLLLIF CEIGICSKAK KLPYQWTVVP LPAKIVAILA DTLLEIQEQV GGDNEDSDWE EVENEDDELL LYLFIRLNNR VILHKFQDDN LGILLLHGPF LPAKSANFHK FYLRQSSLFP I //