ID   A0A540UCZ1_STRSU        Unreviewed;       313 AA.
AC   A0A540UCZ1;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   28-JUN-2023, entry version 16.
DE   SubName: Full=HAMP domain-containing histidine kinase {ECO:0000313|EMBL:TQE82398.1};
GN   ORFNames=FH693_02985 {ECO:0000313|EMBL:TQE82398.1};
OS   Streptococcus suis.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1307 {ECO:0000313|EMBL:TQE82398.1, ECO:0000313|Proteomes:UP000316044};
RN   [1] {ECO:0000313|EMBL:TQE82398.1, ECO:0000313|Proteomes:UP000316044}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2017UMN1435.22 {ECO:0000313|EMBL:TQE82398.1,
RC   ECO:0000313|Proteomes:UP000316044};
RA   Tan S., Dvorak C.M.T., Gebhart C., Estrada A., Marthaler D.G.,
RA   Murtaugh M.P.;
RT   "Comprehensive assessment of Oxford Nanopore MinION sequencing for
RT   bacterial characterization and routine diagnosis.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TQE82398.1}.
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DR   EMBL; VIEI01000001; TQE82398.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A540UCZ1; -.
DR   Proteomes; UP000316044; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   PANTHER; PTHR45453; PHOSPHATE REGULON SENSOR PROTEIN PHOR; 1.
DR   PANTHER; PTHR45453:SF2; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:TQE82398.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          117..313
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   313 AA;  36162 MW;  79A1B5BCDCFB612D CRC64;
     MIAKFIREYR SFYFSYIVLA TSFILLFFLY QLPTEFLQNA LLLSLTFLIL LTVGLFWKFR
     NRMRALEDYV HEEALPLLNK PVDLAYLNLI EAEKEATREQ LLDYKSREED LQAMVKMWSH
     QMKVPLAALS LMSQTDNLNQ QDVNHQLLRL DNYMANLLNY LKLTNHASDF RFEQVEVREV
     VVDLVKKYRN QFLQKDISVT IDGNWLLKTD RKWLSFALSQ IIDNALKYNK TGGKVAIELN
     GGISISDTGI GILAEDIPRL FDEGFTGFNG REHQKATGFG LYLTKRVLNQ LELAISVESQ
     LEVGTTVSIT KVQ
//